Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 5/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 5/20 | 0.51 |
| ▸ | HTR2A | P28223 | 3/20 | 0.51 |
| ▸ | HTR2B | P41595 | 3/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1767672 | 0.74 | TAAR1 (0.42) | HTR6TAAR1HTR2CHTR2AHTR2B | |
| SCHEMBL28839913 | 0.73 | TAAR1 (0.53) | HTR6TAAR1 | |
| SCHEMBL2947725 | 0.71 | MEN1 (0.74) | — | |
| SCHEMBL6164646 | 0.71 | HTR1A (0.60) | HTR6TAAR1HTR2CHTR2AHTR2B | |
| Hydrochloric Acid SCHEMBL9654609 | 0.70 | HTR1A (0.59) | HTR6TAAR1HTR2CHTR2AHTR2B | |
| Hydrochloric Acid SCHEMBL16651431 | 0.70 | TAAR1 (0.94) | TAAR1ACHE | |
| SCHEMBL712846 | 0.69 | TAAR1 (1.00) | TAAR1ACHE | |
| SCHEMBL6665233 | 0.69 | HTR6 (0.68) | HTR6HTR2CACHE | |
| SCHEMBL8705117 | 0.69 | HTR6 (0.49) | HTR6TAAR1HTR2CACHEEPHX2 | |
| SCHEMBL169211 | 0.68 | HTR2C (0.55) | HTR6HTR2CHTR2AEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105683183-A | Substituted pyridine-piperazinyl analogues as RSV antiviral compounds | 爱尔兰詹森科学公司 | 2016-06-15 | — | — | CN | disclosed |