Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 2/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.41 |
| ▸ | HTR3B | O95264 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.41 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9070490 | 0.82 | EPHX2 (0.51) | HTR6EPHX2HTR2CPLD1HTR1A | |
| SCHEMBL9370567 | 0.75 | EPHX2 (0.50) | HTR6EPHX2HTR2CPLD1HTR1A | |
| SCHEMBL10365739 | 0.74 | EPHX2 (0.44) | HTR6EPHX2HTR2CPLD1HTR1A | |
| SCHEMBL3319555 | 0.71 | HTR7 (0.58) | HTR6EPHX2HTR2CPLD1HTR1A | |
| SCHEMBL11300489 | 0.70 | HTR6 (0.51) | HTR6HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL10495676 | 0.70 | HTR2C (0.68) | EPHX2HTR2CPLD1HTR1ASLC6A2 | |
| SCHEMBL11296484 | 0.69 | SIGMAR1 (0.49) | HTR6HTR2CTAAR1HTR1AHTR3E | |
| Hydrochloric Acid SCHEMBL5900848 | 0.69 | EPHX2 (0.50) | EPHX2HTR2CPLD1SLC6A4 | |
| SCHEMBL11300280 | 0.69 | OPRL1 (0.47) | HTR6TAAR1HTR1AHTR3EHTR3B | |
| SCHEMBL28065684 | 0.69 | HTR6 (0.53) | HTR6EPHX2HTR2CTAAR1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5780472-A | ANTITUMOR AGENTS | SAMJIN PHARMACEUTICAZL CO., LTD. (KR) | 1998-07-14 | — | — | US | disclosed |
| EP-0749425-A1 | NEW PIPERAZINE DERIVATIVES AND METHODS FOR THE PREPARATION THEREOF AND COMPOSITIONS CONTAINING THE SAME | SAMJIN PHARM. CO., LTD. (KR) | 1996-12-27 | — | — | EP | disclosed |
| WO-1996021648-A1 | NEW PIPERAZINE DERIVATIVES AND METHODS FOR THE PREPARATION THEREOF AND COMPOSITIONS CONTAINING THE SAME | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 1996-07-18 | — | — | WO | disclosed |