Guaiacol

Guaiacol

SCHEMBL28065829

C=O.CC(C)=O.COc1ccccc1O

nearest known ligand 0.75

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.75
CA2 P00918 3/20 0.75
TP53 P04637 2/20 0.75
TSHR P16473 2/20 0.75
MAPT P10636 4/20 0.54
KDM4E B2RXH2 3/20 0.54
MAPK1 P28482 2/20 0.54
ALDH1A1 P00352 2/20 0.54
LMNA P02545 2/20 0.54
CYP3A4 P08684 1/20 0.54
HPGD P15428 1/20 0.54
ALOX15 P16050 1/20 0.54
ALOX12 P18054 1/20 0.54
HSD17B10 Q99714 1/20 0.54
RAB9A P51151 2/20 0.49
NPC1 O15118 1/20 0.49
ATM Q13315 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
CA12 O43570 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Guaiacol SCHEMBL28032481 0.96 CA1 (0.82) CA1CA2TP53TSHRMAPT
Guaiacol SCHEMBL7134809 0.94 CA1 (0.86) CA1CA2TP53TSHRMAPT
Guaiacol SCHEMBL5665553 0.89 CA1 (0.78) CA1CA2TP53TSHRMAPT
Guaiacol SCHEMBL27557964 0.88 CA1 (0.75) CA1CA2TP53TSHRMAPT
Guaiacol SCHEMBL27709864 0.88 CA1 (0.75) CA1CA2TP53TSHRMAPT
Guaiacol SCHEMBL21542 0.87 CA1 (0.82) CA1CA2TP53TSHRMAPT
Guaiacol SCHEMBL27667858 0.87 CA1 (0.90) CA1CA2TP53TSHRMAPT
Guaiacol SCHEMBL671733 0.87 CA2 (1.00) CA1CA2TP53TSHRMAPT
Guaiacol SCHEMBL29454477 0.87
Guaiacol SCHEMBL21626 0.87

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105575462-B A kind of sulfonated acetone formaldehyde condensation products disperse poly- 3,4 ethylenedioxy thiophene electrically conductive composite and preparation and application 华南理工大学 2017-08-25 CN disclosed
CN-105575462-A Conductive compound prepared by scattering and polymerizing 3,4-ethylenedioxythiophene on sulfonated acetone-formaldehyde condensate as well as preparation method and application of conductive compound UNIV SOUTH CHINA TECH 2016-05-11 CN disclosed