Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14341653 | 0.87 | HPGD (0.46) | MAPK1MAPTRAB9ANPC1MEN1 | |
| SCHEMBL14367054 | 0.80 | L3MBTL1 (0.41) | MAPTKMT2ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL6208993 | 0.78 | NR1H2 (0.48) | TSHRCYP3A4MAPTRAB9ANPC1 | |
| SCHEMBL7518002 | 0.78 | MAPT (0.50) | MAPTKMT2ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL18062414 | 0.78 | CYP3A4 (0.48) | TSHRCYP3A4MAPK1MAPTRAB9A | |
| SCHEMBL10585742 | 0.77 | CYP2C9 (0.42) | MAPK1MAPTMEN1KMT2ALMNA | |
| SCHEMBL5805457 | 0.77 | NOS3 (0.47) | TSHRKMT2ASMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL6038269 | 0.76 | HPGD (0.38) | MAPTKMT2ALMNAALDH1A1HTT | |
| SCHEMBL1157660 | 0.76 | MAPT (0.55) | TSHRMAPTRAB9ANPC1LMNA | |
| SCHEMBL15694511 | 0.76 | CES2 (0.42) | TSHRMAPK1MAPTNPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105579463-A | Mixed mode ligands | BIO RAD LABORATORIES INC | 2016-05-11 | — | — | CN | disclosed |