Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2117185 | 0.80 | CHRM4 (0.38) | ALDH1A1KDM4EHPGDMAPK1 | |
| SCHEMBL10457804 | 0.75 | ALDH1A1 (0.54) | ALDH1A1KDM4EHPGDMAPK1CYP2C9 | |
| SCHEMBL28237349 | 0.70 | SCN9A (0.40) | ALDH1A1KDM4EHPGDCYP2C9CYP2C19 | |
| SCHEMBL24463116 | 0.67 | LMNA (0.43) | ALDH1A1KDM4EHPGDCYP2C9CYP2C19 | |
| SCHEMBL24463449 | 0.66 | CNR2 (0.45) | ALDH1A1KDM4E | |
| SCHEMBL30753426 | 0.63 | KDM4E (0.39) | ALDH1A1KDM4ECYP2C9CYP2C19CYP3A4 | |
| SCHEMBL17378563 | 0.63 | RAB9A (0.45) | ALDH1A1KDM4EHPGDCYP2C9CYP2C19 | |
| SCHEMBL4539855 | 0.63 | SMN1; SMN2 (0.58) | ALDH1A1KDM4EMAPK1LMNANPC1 | |
| SCHEMBL21017338 | 0.62 | KMT2A (0.48) | ALDH1A1KDM4ELMNAMEN1KMT2A | |
| SCHEMBL19836570 | 0.61 | KMT2A (0.47) | ALDH1A1KDM4EHPGDMAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105884693-A | Parasiticidal Compositions Comprising Benzimidazole Derivatives, Methods And Uses Thereof | 梅里亚有限公司 | 2016-08-24 | — | — | CN | disclosed |