SCHEMBL28066136

SCHEMBL28066136

NC(=O)C(N)(CC(=O)O)CC(=O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.39
HMGCR P04035 1/20 0.39
CHRM1 P11229 1/20 0.39
TBXA2R P21731 1/20 0.39
ADRA1A P35348 1/20 0.39
KDM4E B2RXH2 1/20 0.39
CYP2C19 P33261 2/20 0.38
HIF1A Q16665 2/20 0.38
CYP2D6 P10635 1/20 0.38
TSHR P16473 1/20 0.38
GLRA1 P23415 1/20 0.35
SLC6A9 P48067 1/20 0.35
OR51E2 Q9H255 1/20 0.35
MEN1 O00255 1/20 0.34
CYP1A2 P05177 1/20 0.34
THRB P10828 1/20 0.34
KMT2A Q03164 1/20 0.34
CPT2 P23786 2/20 0.33
ACHE P22303 1/20 0.33
FFAR1 O14842 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1101154 0.83 ARG2 (0.40) ALDH1A1HMGCRCHRM1TBXA2RADRA1A
SCHEMBL509976 0.79 ALDH1A1 (0.48) ALDH1A1HMGCRCHRM1TBXA2RADRA1A
SCHEMBL681316 0.77 ALDH1A1 (0.39) ALDH1A1HMGCRCHRM1TBXA2RADRA1A
SCHEMBL10512288 0.76 ALDH1A1 (0.40) ALDH1A1HMGCRCHRM1TBXA2RADRA1A
SCHEMBL10508109 0.72 ALDH1A1 (0.42) ALDH1A1HMGCRCHRM1TBXA2RADRA1A
SCHEMBL10508105 0.72 ALDH1A1 (0.42) ALDH1A1HMGCRCHRM1TBXA2RADRA1A
SCHEMBL3146213 0.72 ARG2 (0.45) ALDH1A1HMGCRCHRM1TBXA2RADRA1A
SCHEMBL3146220 0.72 ARG2 (0.45) ALDH1A1HMGCRCHRM1TBXA2RADRA1A
SCHEMBL26361 0.71 ALDH1A1 (0.45) ALDH1A1HMGCRCHRM1TBXA2RADRA1A
SCHEMBL10589741 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106431889-A Synthesizing method for acetone dicarboxylic acid as atropine drug intermediate 厦门市凯尔利信息科技有限公司 2017-02-22 CN disclosed
CN-105503603-A Method for synthesizing atropine drug intermediate acetonedicarboxylic acid CHENGDU QIANYE LONGHUA PETROLEUM ENG TECH CONSULTING CO LTD 2016-04-20 CN disclosed