SCHEMBL1101154

SCHEMBL1101154

NC(=O)[C@](N)(CCO)CC(=O)O

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ARG2 P78540 2/20 0.40
ARG1 P05089 1/20 0.40
ALDH1A1 P00352 2/20 0.33
MEN1 O00255 1/20 0.33
CYP1A2 P05177 1/20 0.33
THRB P10828 1/20 0.33
KMT2A Q03164 1/20 0.33
KDM4E B2RXH2 1/20 0.32
FFAR1 O14842 1/20 0.32
CPT2 P23786 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
HMGCR P04035 1/20 0.32
CHRM1 P11229 1/20 0.32
TBXA2R P21731 1/20 0.32
ADRA1A P35348 1/20 0.32
CYP2D6 P10635 1/20 0.31
TSHR P16473 1/20 0.31
CYP2C19 P33261 1/20 0.31
HIF1A Q16665 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28066136 0.83 ALDH1A1 (0.39) ALDH1A1MEN1CYP1A2THRBKMT2A
SCHEMBL4470965 0.74 MEN1 (0.43) ARG2ARG1ALDH1A1MEN1CYP1A2
SCHEMBL8995134 0.73 ALDH1A1 (0.36) ARG2ARG1ALDH1A1MEN1CYP1A2
SCHEMBL8168356 0.72 ARG1 (0.63) ARG2ARG1ALDH1A1MEN1CYP1A2
SCHEMBL3095942 0.71 ALDH1A1 (0.35) ARG2ARG1ALDH1A1MEN1CYP1A2
SCHEMBL16936163 0.70 CYP2D6 (0.37) ARG2ARG1ALDH1A1MEN1CYP1A2
SCHEMBL509976 0.69 ALDH1A1 (0.48) ARG2ARG1ALDH1A1MEN1CYP1A2
SCHEMBL3146213 0.69 ARG2 (0.45) ARG2ARG1ALDH1A1MEN1CYP1A2
SCHEMBL3146220 0.69 ARG2 (0.45) ARG2ARG1ALDH1A1MEN1CYP1A2
SCHEMBL4610249 0.68 KDM4E (0.41) ARG2ARG1ALDH1A1KDM4EFFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130251778-A1 MEDICAL DEVICES FOR THERAPEUTIC AGENT DELIVERY WITH POLYMERIC REGIONS THAT CONTAIN COPOLYMERS HAVING BOTH SOFT SEGMENTS AND UNIFORM LENGTH HARD SEGMENTS BOSTON SCIENTIFIC SCIMED, INC. (US) 2013-09-26 US disclosed
US-8538515-B2 Internal medical devices for delivery of therapeutic agent in conjunction with a source of electrical power BOSTON SCIENTIFIC SCIMED, INC. (US) 2013-09-17 US disclosed
EP-1979014-B1 MEDICAL DEVICES FOR THERAPEUTIC AGENT DELIVERY WITH POLYMERIC REGIONS THAT CONTAIN COPOLYMERS HAVING BOTH SOFT SEGMENTS AND UNIFORM LENGTH HARD SEGMENTS BOSTON SCIENT LTD (BB) 2013-07-03 EP disclosed
US-8440214-B2 Medical devices for therapeutic agent delivery with polymeric regions that contain copolymers having both soft segments and uniform length hard segments BOSTON SCIENTIFIC SCIMED, INC. (US) 2013-05-14 US disclosed
EP-1866026-B1 INTERNAL MEDICAL DEVICES FOR DELIVERY OF THERAPEUTIC AGENT IN CONJUNCTION WITH A SOURCE OF ELECTRICAL POWER BOSTON SCIENT LTD (BB) 2013-04-24 EP disclosed
US-8152759-B2 Internal medical devices for delivery of therapeutic agent in conjunction with a source of electrical power BOSTON SCIENTIFIC SCIMED, INC. (US) 2012-04-10 US disclosed
US-20110046539-A1 INTERNAL MEDICAL DEVICES FOR DELIVERY OF THERAPEUTIC AGENT IN CONJUNCTION WITH A SOURCE OF ELECTRICAL POWER BOSTON SCIENTIFIC SCIMED, INC. (US) 2011-02-24 US disclosed
US-7850645-B2 Internal medical devices for delivery of therapeutic agent in conjunction with a source of electrical power BOSTON SCIENTIFIC SCIMED, INC. (US) 2010-12-14 US disclosed
US-20070178136-A1 Medical devices for therapeutic agent delivery with polymeric regions that contain copolymers having both soft segments and uniform length hard segments BOSTON SCIENTIFIC SCIMED, INC. 2007-08-02 US disclosed
US-20060184092-A1 Internal medical devices for delivery of therapeutic agent in conjunction with a source of electrical power BOSTON SCIENTIFIC SCIMED, INC. 2006-08-17 US disclosed