Acrylamide

Acrylamide

SCHEMBL28066609

C=CC(N)=O.[CH2]c1ccccc1

nearest known ligand 0.52

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.52
TSHR P16473 6/20 0.52
FGFR4 P22455 1/20 0.52
AKT1 P31749 1/20 0.48
TGM2 P21980 2/20 0.43
CYP3A4 P08684 3/20 0.42
CYP2C19 P33261 3/20 0.42
MAPT P10636 3/20 0.42
HSD17B10 Q99714 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
POLB P06746 1/20 0.42
PARP1 P09874 1/20 0.42
RECQL P46063 1/20 0.42
BLM P54132 1/20 0.42
PMP22 Q01453 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
HTT P42858 1/20 0.41
CYP2C9 P11712 1/20 0.38
THRB P10828 1/20 0.36
ALOX15 P16050 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL7005540 0.83 TSHR (0.55) ALDH1A1TSHRFGFR4AKT1TGM2
Biphenyl SCHEMBL1539344 0.83 TSHR (0.55) ALDH1A1TSHRFGFR4AKT1TGM2
Benzene SCHEMBL20788779 0.82 ALDH1A1 (0.79) ALDH1A1TSHRFGFR4AKT1TGM2
Aniline SCHEMBL28168391 0.81 TSHR (0.52) ALDH1A1TSHRFGFR4AKT1TGM2
Phenol SCHEMBL4024542 0.81 TDP1 (0.52) ALDH1A1TSHRFGFR4AKT1TGM2
Naphthalene SCHEMBL28218080 0.80 ALDH1A1 (0.58) ALDH1A1TSHRFGFR4AKT1TGM2
Acrylamide SCHEMBL28163520 0.80 TSHR (0.58) ALDH1A1TSHRFGFR4AKT1TGM2
Phenol SCHEMBL10484564 0.79 TDP1 (0.50) ALDH1A1TSHRFGFR4AKT1TGM2
Benzoic Acid SCHEMBL3718190 0.79 TSHR (0.64) ALDH1A1TSHRFGFR4AKT1CYP3A4
Acrylamide SCHEMBL5011667 0.79 TSHR (0.50) ALDH1A1TSHRFGFR4AKT1TGM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105911816-A Curable composition comprising quantum dot color, filter manufactured using thereof and image display device having the same 东友精细化工有限公司 2016-08-31 CN disclosed