Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.55 |
| ▸ | AKT1 | P31749 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TGM2 | P21980 | 1/20 | 0.45 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 2/20 | 0.44 |
| ▸ | IKBKB | O14920 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biphenyl SCHEMBL1539344 | 1.00 | TSHR (0.55) | TSHRALDH1A1FGFR4AKT1LMNA | |
| Acrylamide SCHEMBL3491747 | 0.88 | EGFR (0.55) | TSHRMAPTDHODHTP53EGFR | |
| Acrylamide SCHEMBL3331475 | 0.87 | ALDH1A1 (0.65) | TSHRALDH1A1FGFR4AKT1LMNA | |
| Biphenyl SCHEMBL1311763 | 0.84 | LMNA (0.56) | TSHRALDH1A1AKT1LMNATGM2 | |
| Biphenyl SCHEMBL36309 | 0.84 | LMNA (0.56) | TSHRALDH1A1AKT1LMNATGM2 | |
| Benzene SCHEMBL20788779 | 0.84 | ALDH1A1 (0.79) | TSHRALDH1A1FGFR4AKT1LMNA | |
| Phenol SCHEMBL4024542 | 0.83 | TDP1 (0.52) | TSHRALDH1A1FGFR4AKT1LMNA | |
| Aniline SCHEMBL28168391 | 0.83 | TSHR (0.52) | TSHRALDH1A1FGFR4AKT1LMNA | |
| Acrylamide SCHEMBL28066609 | 0.83 | ALDH1A1 (0.52) | TSHRALDH1A1FGFR4AKT1LMNA | |
| Naphthalene SCHEMBL28218080 | 0.82 | ALDH1A1 (0.58) | TSHRALDH1A1FGFR4AKT1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0860438-A1 | Fluorine-containing diphenyl acrylamide antimicrobial agents | Shenyang Research Institute of Chemical Industry (CN) | 1998-08-26 | — | — | EP | claimed |
| CN-1167568-A | Fungicide contg. fluorodiphenyl acrylamides | SHENYANG CHEM INST MINISTRY OF (CN) | 1997-12-17 | — | — | CN | claimed |
| CN-1155977-A | Acrylamide germicide containing fluoro-diphenyl | SHENYANG CHEMICAL INST MINISTR (CN) | 1997-08-06 | — | — | CN | claimed |
| CN-108276376-B | Novel diphenylpropenes derivative, preparation method thereof and pharmaceutical composition | 北京理工大学 | 2020-06-05 | — | — | CN | disclosed |
| WO-2019203786-A1 | TEXTILE PRINTING | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) | 2019-10-24 | — | — | WO | disclosed |
| EP-3046902-B1 | COMPOSITIONS FOR THE TREATMENT OF HYPERTENSION AND/OR FIBROSIS | VECTUS BIOSYSTEMS LTD (AU) | 2018-08-08 | — | — | EP | disclosed |
| US-9630935-B2 | Compositions for the treatment of hypertension and/or fibrosis | VECTUS BIOSYSTEMS LIMITED (AU) | 2017-04-25 | — | — | US | disclosed |
| US-20160280671-A1 | COMPOSITIONS FOR THE TREATMENT OF HYPERTENSION AND/OR FIBROSIS | VECTUS BIOSYSTEMS LIMITED (AU) | 2016-09-29 | — | — | US | disclosed |
| CN-105683153-A | Compositions for the treatment of hypertension and/or fibrosis | 维克图斯生物系统有限公司 | 2016-06-15 | — | — | CN | disclosed |
| CN-103890014-B | For the emulsifying agent of letex polymerization | DAI-ICHI KOGYO SEIYAKU CO.,LTD. (JP) | 2016-01-20 | — | — | CN | disclosed |
| CN-1163141-C | Sterilizing agent composition | 沈阳化工研究院 | 2004-08-25 | — | — | CN | disclosed |
| US-6020332-A | Fluorine-containing diphenyl acrylamide antimicrobial agents | SHENYANG RESEARCH INSTITUTE OF CHEMICAL INDUSTRY (CN) | 2000-02-01 | — | — | US | disclosed |
| US-6020332-A | Fluorine-containing diphenyl acrylamide antimicrobial agents | SHENYANG RESEARCH INSTITUTE OF CHEMICAL INDUSTRY (CN) | 2000-02-01 | — | — | US | disclosed |
| EP-0860438-A1 | Fluorine-containing diphenyl acrylamide antimicrobial agents | Shenyang Research Institute of Chemical Industry (CN) | 1998-08-26 | — | — | EP | disclosed |
| EP-0860438-A1 | Fluorine-containing diphenyl acrylamide antimicrobial agents | Shenyang Research Institute of Chemical Industry (CN) | 1998-08-26 | — | — | EP | disclosed |
| EP-0860438-A1 | Fluorine-containing diphenyl acrylamide antimicrobial agents | Shenyang Research Institute of Chemical Industry (CN) | 1998-08-26 | — | — | EP | disclosed |
| CN-1167568-A | Fungicide contg. fluorodiphenyl acrylamides | SHENYANG CHEM INST MINISTRY OF (CN) | 1997-12-17 | — | — | CN | disclosed |
| CN-1155977-A | Acrylamide germicide containing fluoro-diphenyl | SHENYANG CHEMICAL INST MINISTR (CN) | 1997-08-06 | — | — | CN | disclosed |
| US-4151148-A | ADDITION-CONDENSATION COPOLYMERS | ICI AMERICAS INC. (US) | 1979-04-24 | — | — | US | disclosed |
| US-4012353-A | CATIONIC POLYMER BINDERS | ICI UNITED STATES INC. (US) | 1977-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160280671-A1 | COMPOSITIONS FOR THE TREATMENT OF HYPERTENSION AND/OR FIBROSIS | TGFB1, REN, TGFB2 | TSHR 3566/4885ALDH1A1 1172/4885FGFR4 567/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.