⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4235047 | 0.77 | LMNA (0.32) | — | |
| SCHEMBL28362034 | 0.72 | — | — | |
| SCHEMBL7771682 | 0.72 | — | — | |
| SCHEMBL27703464 | 0.70 | STAT3 (0.32) | — | |
| SCHEMBL28829032 | 0.69 | TRPA1 (0.33) | — | |
| SCHEMBL27455884 | 0.68 | — | — | |
| SCHEMBL7192159 | 0.67 | MAOA (0.34) | — | |
| SCHEMBL2382929 | 0.66 | POLB (0.32) | — | |
| SCHEMBL2236006 | 0.65 | TSHR (0.39) | — | |
| SCHEMBL31008990 | 0.65 | AKT1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110590798-A | Process for producing cyclobutanetetracarboxylic acid derivative | 日产化学工业株式会社 | 2019-12-20 | — | — | CN | disclosed |
| CN-110105367-A | The manufacturing method of cyclobutane tetracarboxylic acid derivatives | 日产化学工业株式会社 | 2019-08-09 | — | — | CN | disclosed |
| CN-105916865-B | Process for producing cyclobutanetetracarboxylic acid derivative | 日产化学工业株式会社 | 2019-06-25 | — | — | CN | disclosed |
| CN-105916863-B | The manufacturing method of 1,3- dialkyl cyclic butane -1,2,3,4- tetrabasic carboxylic acid -1,2:3,4- dianhydride | 日产化学工业株式会社 | 2019-03-01 | — | — | CN | disclosed |
| CN-105916863-A | Method for producing high purity 1,3-dialkyl cyclobutane-1,2,3,4-tetracarboxylic acid-1,2:3,4-di-anhydride | 日产化学工业株式会社 | 2016-08-31 | — | — | CN | disclosed |
| CN-105916865-A | Process for producing cyclobutanetetracarboxylic acid derivative | 日产化学工业株式会社 | 2016-08-31 | — | — | CN | disclosed |
| CN-105916866-A | Process for producing cyclobutanetetracarboxylic acid derivative | 日产化学工业株式会社 | 2016-08-31 | — | — | CN | disclosed |
| CN-105916864-A | Method for producing cyclobutane tetracarboxylic acid derivative | 日产化学工业株式会社 | 2016-08-31 | — | — | CN | disclosed |
| CN-105916867-A | Process for producing cyclobutanetetracarboxylic acid derivative | 日产化学工业株式会社 | 2016-08-31 | — | — | CN | disclosed |