Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | ATM | Q13315 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | CCR6 | P51684 | 1/20 | 0.47 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.47 |
| ▸ | CDC25B | P30305 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.43 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2913778 | 0.89 | AKR1C3 (0.48) | AKR1C3GAAMAPTALDH1A1ATM | |
| SCHEMBL11072642 | 0.88 | AKR1C3 (0.47) | AKR1C3GAAMAPTALDH1A1ATM | |
| SCHEMBL7979358 | 0.88 | AKR1C3 (0.47) | AKR1C3GAAMAPTALDH1A1ATM | |
| SCHEMBL19243893 | 0.88 | AKR1C3 (0.47) | AKR1C3GAAMAPTALDH1A1ATM | |
| SCHEMBL10828176 | 0.85 | AKR1C3 (0.44) | AKR1C3GAAMAPTALDH1A1ATM | |
| SCHEMBL27347082 | 0.85 | AKR1C3 (0.57) | AKR1C3GAAMAPTALDH1A1ATM | |
| SCHEMBL1200740 | 0.80 | AKR1C3 (0.55) | AKR1C3GAAMAPTALDH1A1ATM | |
| SCHEMBL11120199 | 0.78 | NPSR1 (0.47) | AKR1C3GAAMAPTALDH1A1ATM | |
| SCHEMBL29447165 | 0.78 | AKR1C3 (0.85) | AKR1C3GAAMAPTALDH1A1ATM | |
| SCHEMBL700595 | 0.78 | AKR1C3 (0.85) | AKR1C3GAAMAPTALDH1A1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110590798-A | Process for producing cyclobutanetetracarboxylic acid derivative | 日产化学工业株式会社 | 2019-12-20 | — | — | CN | disclosed |
| CN-110105367-A | The manufacturing method of cyclobutane tetracarboxylic acid derivatives | 日产化学工业株式会社 | 2019-08-09 | — | — | CN | disclosed |
| CN-105916865-B | Process for producing cyclobutanetetracarboxylic acid derivative | 日产化学工业株式会社 | 2019-06-25 | — | — | CN | disclosed |
| CN-105916866-B | Process for producing cyclobutanetetracarboxylic acid derivative | 日产化学工业株式会社 | 2018-08-28 | — | — | CN | disclosed |
| CN-105916865-A | Process for producing cyclobutanetetracarboxylic acid derivative | 日产化学工业株式会社 | 2016-08-31 | — | — | CN | disclosed |
| CN-105916866-A | Process for producing cyclobutanetetracarboxylic acid derivative | 日产化学工业株式会社 | 2016-08-31 | — | — | CN | disclosed |
| CN-105916867-A | Process for producing cyclobutanetetracarboxylic acid derivative | 日产化学工业株式会社 | 2016-08-31 | — | — | CN | disclosed |