SCHEMBL1200740

SCHEMBL1200740

N#Cc1ccccc1C(=O)c1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 2/20 0.55
GAA P10253 1/20 0.52
MAPT P10636 1/20 0.52
NPSR1 Q6W5P4 2/20 0.51
ALDH1A1 P00352 2/20 0.50
ATM Q13315 3/20 0.47
TDP1 Q9NUW8 2/20 0.47
HSP90AA1 P07900 1/20 0.47
PKM P14618 1/20 0.47
CCR6 P51684 1/20 0.47
TLR9 Q9NR96 1/20 0.47
CES2 O00748 2/20 0.44
CES1 P23141 2/20 0.44
CDC25B P30305 1/20 0.44
POLB P06746 2/20 0.44
L3MBTL1 Q9Y468 1/20 0.43
SRD5A2 P31213 1/20 0.43
CNR2 P34972 1/20 0.43
LMNA P02545 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2913776 0.87 ALDH1A1 (0.45) GAAMAPTNPSR1ALDH1A1POLB
SCHEMBL9856394 0.87 AKR1C3 (0.41) AKR1C3GAAMAPTNPSR1ALDH1A1
SCHEMBL9798109 0.87 LIG1 (0.59) AKR1C3GAAMAPTNPSR1ATM
SCHEMBL9797365 0.85 LIG1 (0.41) AKR1C3GAAMAPTNPSR1ALDH1A1
SCHEMBL7559438 0.85 AKR1C3 (0.48) AKR1C3GAAMAPTNPSR1ALDH1A1
SCHEMBL2913778 0.85 AKR1C3 (0.48) AKR1C3GAAMAPTNPSR1ALDH1A1
SCHEMBL9589641 0.85 AKR1C3 (0.59) AKR1C3GAAMAPTALDH1A1TDP1
Benzophenone SCHEMBL17818513 0.85 ALDH1A1 (0.64) AKR1C3GAAMAPTNPSR1ALDH1A1
SCHEMBL15209960 0.84 CES2 (0.56) GAAMAPTNPSR1ALDH1A1ATM
SCHEMBL27532725 0.84 AKR1C3 (0.47) AKR1C3GAAMAPTNPSR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113862708-A Method for electrochemically synthesizing beta-cyano-bis-phenylsulfonyl imide compound 常州工学院 2021-12-31 CN claimed
CN-118851893-A New synthetic method of diaryl ketone derivative 河南大学 2024-10-29 CN disclosed
CN-113862708-B Method for electrochemically synthesizing beta-cyano bis-benzenesulfonimide compound 常州工学院 2023-09-01 CN disclosed
CN-113957462-A Synthesis method of beta-cyano ketone compound 常州工学院 2022-01-21 CN disclosed
CN-113862708-A Method for electrochemically synthesizing beta-cyano-bis-phenylsulfonyl imide compound 常州工学院 2021-12-31 CN disclosed
CN-113862708-A Method for electrochemically synthesizing beta-cyano-bis-phenylsulfonyl imide compound 常州工学院 2021-12-31 CN disclosed
EP-3162799-B1 FLUOROALKYLATING AGENT KUMIAI CHEMICAL INDUSTRY CO (JP) 2021-03-10 EP disclosed
US-10696640-B2 Fluoroalkylating agent KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2020-06-30 US disclosed
CN-110590798-A Process for producing cyclobutanetetracarboxylic acid derivative 日产化学工业株式会社 2019-12-20 CN disclosed
CN-110105367-A The manufacturing method of cyclobutane tetracarboxylic acid derivatives 日产化学工业株式会社 2019-08-09 CN disclosed
CN-1103781-A Use of phenalkylamines HOFFMANN LA ROCHE (CH) 1995-06-21 CN disclosed
EP-0575425-A1 USE OF OXAZOLO- 2,3-a]ISOINDOLE AND IMIDAZO 2,1-a]ISOINDOLE DERIVATIVES AS ANTIVIRAL DRUGS, AND NEW OXAZOLO 2,3-a]ISOINDOLE DERIVATIVES. BOEHRINGER MANNHEIM GMBH (DE) 1993-12-29 EP disclosed
WO-1993015086-A1 HIGHLY REACTIVE FORMS OF ZINC AND REAGENTS THEREOF BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) 1993-08-05 WO disclosed
WO-1992016207-A1 USE OF OXAZOLO-[2,3-a]ISOINDOLE AND IMIDAZO[2,1-a]ISOINDOLE DERIVATIVES AS ANTIVIRAL DRUGS, AND NEW OXAZOLO[2,3-a]ISOINDOLE DERIVATIVES BOEHRINGER MANNHEIM GMBH (DE) 1992-10-01 WO disclosed
EP-0408509-A2 Substituted benzonitriles CIBA-GEIGY AG (CH) 1991-01-16 EP disclosed
US-4717479-A Hydrophilized porous polyolefin membrane and production process thereof MITSUBISHI RAYON CO., LTD. (JP) 1988-01-05 US disclosed
US-4678813-A GRAFT POLYMERIZING SURFACTANT ON WALLS MITSUBISHI RAYON CO., LTD. (JP) 1987-07-07 US disclosed
EP-0222365-A2 Hydrophilized porous polyolefin membrane and production process thereof MITSUBISHI RAYON CO., LTD. (JP) 1987-05-20 EP disclosed
US-4175945-A PLANT GROWTH REGULATORS FOR TABACCO ROHM AND HAAS COMPANY (US) 1979-11-27 US disclosed
US-4120687-A CONTROLLING GROWTH OF TOBACCO SUCKERS MEISINGER ROBERT H 1978-10-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10696640-B2 Fluoroalkylating agent AFF1, AFF4, AFF2 AKR1C3 63/4885GAA 1685/4885MAPT 4841/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.