1,2-Dichlorobenzene

1,2-Dichlorobenzene

SCHEMBL28067053

COC=O.Clc1ccccc1Cl

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.53
LMNA P02545 2/20 0.53
ALDH1A1 P00352 5/20 0.44
KMT2A Q03164 2/20 0.44
MEN1 O00255 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
NFE2L2 Q16236 4/20 0.38
RELA Q04206 1/20 0.38
ERN1 O75460 1/20 0.38
CES2 O00748 1/20 0.37
CES1 P23141 1/20 0.37
MAOB P27338 2/20 0.37
KCNH2 Q12809 1/20 0.36
GAA P10253 1/20 0.36
HTT P42858 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formic Acid Methyl Ester SCHEMBL25291105 0.77 NFE2L2 (0.41) LMNAALDH1A1KMT2AMEN1TDP1
Anthracene SCHEMBL32670790 0.74 CYP2A6 (0.46) LMNAALDH1A1TDP1ERN1HTT
Formic Acid Methyl Ester SCHEMBL28758147 0.74 ALDH1A1 (0.47) LMNAALDH1A1KMT2AHTT
Toluene SCHEMBL4302343 0.74 ACHE (0.58) TSHRLMNAALDH1A1KMT2AMEN1
1,2-Dichlorobenzene SCHEMBL28433310 0.73 TSHR (0.83) TSHRLMNAALDH1A1CES2CES1
1,2-Dichlorobenzene SCHEMBL29350623 0.72
1,2-Dichlorobenzene SCHEMBL5190 0.72
1,2-Dichlorobenzene SCHEMBL10593125 0.72
1,2-Dichlorobenzene SCHEMBL1155123 0.72 TSHR (1.00) TSHRLMNAALDH1A1KMT2AMEN1
1,2-Dichlorobenzene SCHEMBL28852872 0.72 TSHR (0.59) TSHRLMNAALDH1A1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108929396-A A kind of rare-earth metal catalyst system and the method for preparing high-cis conjugated diene polymer 北京化工大学 2018-12-04 CN claimed
CN-106995517-B A kind of stereoregular styrene analog thermoplastic elastomer and preparation method thereof 北京化工大学 2019-06-18 CN disclosed
CN-103988127-B Photosensitive resin composition, method for producing cured relief pattern, semiconductor device, and display device 旭化成株式会社 2019-04-19 CN disclosed
CN-108929396-A A kind of rare-earth metal catalyst system and the method for preparing high-cis conjugated diene polymer 北京化工大学 2018-12-04 CN disclosed
CN-108347943-A HEPATITIS B CORE PROTEIN MODULATORS 组装生物科学股份有限公司 2018-07-31 CN disclosed
CN-108250327-A Siliceous functionalized polymeric with hydroxyl of a kind of end of the chain and preparation method thereof and branched polymer 北京化工大学 2018-07-06 CN disclosed
CN-108250371-A Bonding type polymer/silicon dioxide hybrid materials and preparation method thereof 北京化工大学 2018-07-06 CN disclosed
CN-107329367-A Photosensitive resin composition, method for producing cured relief pattern, semiconductor device, and display device 旭化成株式会社 2017-11-07 CN disclosed
CN-106995517-A A kind of stereoregular styrene analog thermoplastic elastomer and preparation method thereof 北京化工大学 2017-08-01 CN disclosed
CN-106232582-A Aryl and heteroaryl ether compound as ROR gamma modulators 格兰马克药品股份有限公司 2016-12-14 CN disclosed
CN-104292224-B Containing replacing 1,3,4-thiophene () diazole thioether benzothiazole amide derivatives and its preparation method and application 贵州大学 2016-07-06 CN disclosed