Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CTSA | P10619 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 2/20 | 0.32 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.30 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL162258 | 0.80 | KMT2A (0.33) | RAB9A | |
| SCHEMBL5637225 | 0.78 | HSD11B1 (0.39) | CTSSHSD11B1 | |
| SCHEMBL16829403 | 0.74 | CTSS (0.44) | CTSSHSD11B1ARSMN1; SMN2PGR | |
| SCHEMBL17514495 | 0.72 | AKR1C3 (0.43) | SMN1; SMN2NPSR1F2RL3 | |
| SCHEMBL3645412 | 0.71 | CTSA (0.33) | CTSAHSD11B1RAB9ASMN1; SMN2 | |
| SCHEMBL2086754 | 0.70 | RAB9A (0.36) | RAB9ASMN1; SMN2F2RL3 | |
| SCHEMBL3289120 | 0.70 | HSD11B1 (0.41) | HSD11B1SCN9AARTRPA1TRPM8 | |
| SCHEMBL15637317 | 0.69 | RPS6KA2 (0.35) | F2RL3 | |
| SCHEMBL8125843 | 0.69 | KMT2A (0.40) | ARRAB9ASMN1; SMN2PGR | |
| SCHEMBL2782878 | 0.69 | CTSA (0.44) | CTSAHSD11B1SCN9ARAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103153999-B | Compounds as cannabinoid receptor-1 inhibitors | AMOREPACIFIC CORP. (KR) | 2016-06-01 | — | — | CN | disclosed |