Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL28067962

N.O=C1C=C(c2ccc(Cl)cc2Cl)C(=O)N1

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPOX P50336 1/20 0.47
CES1 P23141 3/20 0.43
TGM2 P21980 1/20 0.40
AHR P35869 1/20 0.39
S100A4 P26447 1/20 0.38
MAPT P10636 2/20 0.38
CHEK1 O14757 1/20 0.38
ALDH1A1 P00352 1/20 0.38
GSK3A P49840 3/20 0.38
GSK3B P49841 3/20 0.38
MEN1 O00255 1/20 0.38
RGS12 O14924 1/20 0.38
GMNN O75496 1/20 0.38
USP2 O75604 1/20 0.38
CCNB2 O95067 1/20 0.38
LMNA P02545 1/20 0.38
TP53 P04637 1/20 0.38
CYP1A2 P05177 1/20 0.38
CDK1 P06493 1/20 0.38
POLB P06746 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27322030 0.98 PPOX (0.48) PPOXCES1TGM2AHRS100A4
SCHEMBL10682285 0.83 TDP2 (0.36) PPOXCES1AHRMAPTCHEK1
SCHEMBL10585012 0.80 TGM2 (0.40) PPOXCES1TGM2MAPTCYP3A4
SCHEMBL29576852 0.80 CES1 (0.35) PPOXCES1AHRMAPK1PTPN11
Ammonia Solution, Strong SCHEMBL27960588 0.79 PTPRC (0.49) CES1MAPTALDH1A1GSK3AGSK3B
SCHEMBL11322531 0.78 CES1 (0.42) PPOXCES1AHRMAPTALDH1A1
SCHEMBL187280 0.77 PTPRC (0.50) CES1MAPTALDH1A1GSK3AGSK3B
SCHEMBL11372764 0.76 CES1 (0.41) PPOXCES1TGM2S100A4ALDH1A1
SCHEMBL465066 0.76 CES1 (0.47) PPOXCES1AHRALDH1A1MEN1
SCHEMBL27517095 0.75 CES1 (0.46) PPOXCES1AHRMAPTCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103897281-B Thermoplastic resin composition and molded article CHI MEI CORP. (CN) 2016-05-11 CN disclosed