Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 9/20 | 0.56 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.49 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.49 |
| ▸ | NAMPT | P43490 | 3/20 | 0.44 |
| ▸ | AXL | P30530 | 3/20 | 0.43 |
| ▸ | KIF20A | O95235 | 1/20 | 0.41 |
| ▸ | CLK1 | P49759 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.40 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.40 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.40 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8932706 | 0.76 | NR4A2 (0.64) | NR4A2MAP2K1CREBBPNAMPTAXL | |
| SCHEMBL28068053 | 0.75 | CCNT1 (0.49) | NAMPTHTR6 | |
| SCHEMBL31753965 | 0.74 | NR4A2 (0.62) | NR4A2MAP2K1CREBBPAXLDYRK1A | |
| SCHEMBL1607800 | 0.74 | NR4A2 (0.62) | NR4A2MAP2K1CREBBPAXLDYRK1A | |
| SCHEMBL27957959 | 0.72 | NR4A2 (0.71) | NR4A2CREBBP | |
| SCHEMBL26701081 | 0.71 | AXL (0.63) | NR4A2MAP2K1CREBBPAXL | |
| SCHEMBL6588128 | 0.70 | NR4A2 (1.00) | NR4A2MAP2K1CREBBP | |
| SCHEMBL31048762 | 0.70 | NR4A2 (0.72) | NR4A2MAP2K1CREBBP | |
| SCHEMBL6418495 | 0.70 | NR4A2 (0.72) | NR4A2CREBBP | |
| SCHEMBL2434449 | 0.70 | NR4A2 (0.72) | NR4A2MAP2K1CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105612150-B | Sulfonylindole derivatives and process for producing the same | 株式会社大熊制药 | 2018-04-10 | — | — | CN | claimed |
| CN-105612150-A | Sulfonylindole derivatives and process for producing the same | DAE WOONG PHARMA | 2016-05-25 | — | — | CN | claimed |
| CN-105612150-B | Sulfonylindole derivatives and process for producing the same | 株式会社大熊制药 | 2018-04-10 | — | — | CN | disclosed |
| CN-105612150-A | Sulfonylindole derivatives and process for producing the same | DAE WOONG PHARMA | 2016-05-25 | — | — | CN | disclosed |