Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 11/20 | 0.64 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | AXL | P30530 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27957959 | 0.90 | NR4A2 (0.71) | NR4A2CREBBPHSD17B10MEN1POLB | |
| SCHEMBL25405774 | 0.79 | NR4A2 (1.00) | NR4A2CREBBPAXLMAP2K1 | |
| SCHEMBL31083673 | 0.79 | NR4A2 (1.00) | NR4A2CREBBPAXLMAP2K1 | |
| SCHEMBL28068101 | 0.76 | NR4A2 (0.56) | NR4A2CREBBPAXLNAMPTHTR6 | |
| SCHEMBL10396334 | 0.76 | NR4A2 (0.67) | NR4A2CREBBPMEN1KMT2AAXL | |
| SCHEMBL1093530 | 0.76 | NR4A2 (1.00) | NR4A2CREBBPMEN1KMT2AMAPT | |
| SCHEMBL30031033 | 0.76 | NR4A2 (1.00) | NR4A2CREBBPMEN1KMT2AMAPT | |
| SCHEMBL6087545 | 0.75 | NR4A2 (0.66) | NR4A2CREBBPMEN1CYP1A2KMT2A | |
| SCHEMBL4485057 | 0.75 | NR4A2 (0.68) | NR4A2CREBBPHSD17B10MEN1KMT2A | |
| SCHEMBL4240354 | 0.75 | NR4A2 (1.00) | NR4A2CREBBPHSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996026207-A1 | THIAZOLIDINE AND OXAZOLIDINE INDOLES WITH HYPOCLYCEMIC ACTIVITY | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1996-08-29 | — | — | WO | disclosed |