Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | FABP4 | P15090 | 2/20 | 0.42 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.42 |
| ▸ | FABP3 | P05413 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | DHODH | Q02127 | 3/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28068483 | 0.90 | PRNP (0.40) | KDM4ERCE1ALDH1A1HPGDPOLB | |
| SCHEMBL28068267 | 0.87 | FABP4 (0.45) | KDM4ERCE1ALDH1A1HPGDPOLB | |
| SCHEMBL28068260 | 0.86 | AR (0.46) | ALDH1A1HPGDSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL7664295 | 0.84 | LMNA (0.45) | KDM4ERCE1ALDH1A1HPGDPOLB | |
| SCHEMBL28184860 | 0.82 | PDE10A (0.47) | KDM4EALDH1A1HPGDFABP4FABP3 | |
| SCHEMBL28068357 | 0.81 | KMT2A (0.45) | KDM4EALDH1A1HPGDFABP4FABP5 | |
| SCHEMBL8966505 | 0.80 | HMGB1 (0.41) | KDM4EALDH1A1HPGDPOLBDHODH | |
| SCHEMBL28068405 | 0.78 | LDHA (0.40) | KDM4EALDH1A1HPGDFABP4FABP5 | |
| SCHEMBL2356921 | 0.78 | DHODH (0.50) | KDM4ERCE1ALDH1A1HPGDFABP4 | |
| SCHEMBL10905133 | 0.78 | LDHA (0.43) | KDM4EALDH1A1HPGDPDE10ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105566110-B | A kind of synthetic method of polysubstituted 1 naphthols and its derivative | 南开大学 | 2017-10-20 | — | — | CN | disclosed |
| CN-105566110-A | Synthesis method of polysubstituted 1-naphthol and derivatives thereof | UNIV NANKAI | 2016-05-11 | — | — | CN | disclosed |