SCHEMBL4830396

SCHEMBL4830396

CCOC(=O)c1cc(-c2ccccc2)c(C(=O)OCC)cc1-c1ccccc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.63
ALDH1A1 P00352 11/20 0.58
SMN1; SMN2 Q16637 8/20 0.58
HPGD P15428 7/20 0.58
MAPT P10636 6/20 0.57
RAB9A P51151 6/20 0.57
HSD17B10 Q99714 4/20 0.57
GAA P10253 3/20 0.57
ALOX15 P16050 1/20 0.57
NPC1 O15118 5/20 0.53
NFKB1 P19838 2/20 0.53
NFKB2 Q00653 2/20 0.53
RELA Q04206 2/20 0.53
LMNA P02545 3/20 0.52
MAPK1 P28482 2/20 0.52
ATM Q13315 1/20 0.52
KDM4E B2RXH2 5/20 0.52
NPSR1 Q6W5P4 2/20 0.52
TDP1 Q9NUW8 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12354658 0.92 TSHR (0.54) TSHRALDH1A1SMN1; SMN2HPGDMAPT
SCHEMBL6852156 0.91 TSHR (0.53) TSHRALDH1A1SMN1; SMN2HPGDMAPT
SCHEMBL12647490 0.91 TSHR (0.53) TSHRALDH1A1SMN1; SMN2HPGDMAPT
SCHEMBL29015141 0.90 TSHR (0.56) TSHRALDH1A1SMN1; SMN2HPGDMAPT
SCHEMBL20806393 0.89 TSHR (0.51) TSHRALDH1A1SMN1; SMN2HPGDMAPT
SCHEMBL20806414 0.88 TSHR (0.50) TSHRALDH1A1SMN1; SMN2HPGDMAPT
SCHEMBL20806415 0.88 CYP1A2 (0.53) TSHRALDH1A1SMN1; SMN2HPGDMAPT
SCHEMBL14901089 0.87 KDM4E (0.61) TSHRALDH1A1SMN1; SMN2HPGDMAPT
SCHEMBL24684732 0.86 TSHR (0.47) TSHRALDH1A1SMN1; SMN2HPGDMAPT
SCHEMBL20799797 0.86 TP53 (0.51) TSHRALDH1A1SMN1; SMN2HPGDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12629654-B2 Concentration of chemical species through the use of photosenstive sorbent materials GENESIS SYSTEMS LLC (US) 2026-05-19 US disclosed
US-20250196095-A1 CONCENTRATION OF CHEMICAL SPECIES THROUGH THE USE OF PHOTOSENSTIVE SORBENT MATERIALS GENESIS SYSTEMS LLC 2025-06-19 US disclosed
US-20250197653-A1 MODULATING OBJECT SIGNATURES THROUGH THE USE OF PHOTOSENSTIVE SORBENT COATINGS GENESIS SYSTEMS LLC 2025-06-19 US disclosed
US-9246103-B2 Polymers and oligomers with functionalized side groups MERCK PATENT GMBH (DE) 2016-01-26 US disclosed
US-9246103-B2 Polymers and oligomers with functionalized side groups MERCK PATENT GMBH (DE) 2016-01-26 US disclosed
US-8860007-B2 Aryl-substituted polyindenofluorenes for use in organic electroluminiscent devices MERCK PATENT GMBH (DE) 2014-10-14 US disclosed
US-8860007-B2 Aryl-substituted polyindenofluorenes for use in organic electroluminiscent devices MERCK PATENT GMBH (DE) 2014-10-14 US disclosed
US-20140175421-A1 POLYMERS AND OLIGOMERS WITH FUNCTIONALIZED SIDE GROUPS MERCK PATENT GMBH (DE) 2014-06-26 US disclosed
US-20140175421-A1 POLYMERS AND OLIGOMERS WITH FUNCTIONALIZED SIDE GROUPS MERCK PATENT GMBH (DE) 2014-06-26 US disclosed
US-8475936-B2 Organic compound and organic electroluminescence device employing the same INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2013-07-02 US disclosed
WO-2013013753-A2 POLYMERS AND OLIGOMERS WITH FUNCTIONALIZED SIDE GROUPS MERCK PATENT GMBH (DE) 2013-01-31 WO disclosed
US-7329651-B2 Cannabimimetic ligands UNIVERSITY OF CONNECTICUT (US) 2008-02-12 US disclosed
US-7041388-B1 Substituted poly(arylene vinylenes), process for their preparation and their use in electroluminescent devices SEMICONDUCTORS GMBH (DE) 2006-05-09 US disclosed
EP-1232225-B1 SUBSTITUTED POLY(ARYLENE VINYLENES), METHOD FOR THE PRODUCTION THEREOF AND THEIR USE IN ELECTROLUMINESCENT DEVICES COVION ORGANIC SEMICONDUCTORS (DE) 2004-12-01 EP disclosed
US-20040077649-A1 Novel cannabimimetic ligands CONNECTICUT, UNIVERSITY OF 2004-04-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12629654-B2 Concentration of chemical species through the use of photosenstive sorbent materials TRPV4, TRPA1, TRPM4 TSHR 151/4885ALDH1A1 890/4885SMN1; SMN2 4215/4885
US-20040077649-A1 Novel cannabimimetic ligands CNR2, CNR1, GPR18 TSHR 1318/4885ALDH1A1 3461/4885SMN1; SMN2 2671/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.