Phenol

Phenol

SCHEMBL28068525

O=[N+]([O-])c1c(Cl)cccc1Cl.Oc1ccccc1

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIN2D O15399 1/20 0.46
GRIN3B O60391 1/20 0.46
GRIN1 Q05586 1/20 0.46
GRIN2A Q12879 1/20 0.46
GRIN2B Q13224 1/20 0.46
GRIN2C Q14957 1/20 0.46
GRIN3A Q8TCU5 1/20 0.46
ALDH1A1 P00352 4/20 0.46
TSHR P16473 3/20 0.46
ALOX15 P16050 1/20 0.46
GPR35 Q9HC97 2/20 0.44
S100A4 P26447 1/20 0.44
TDP1 Q9NUW8 2/20 0.42
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
GLA P06280 1/20 0.42
CA3 P07451 1/20 0.42
CA4 P22748 1/20 0.42
CA9 Q16790 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenol SCHEMBL27326130 0.90 GPR35 (0.56) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL670917 0.85 TSHR (0.58) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
Toluene SCHEMBL28853124 0.81 ALDH1A1 (0.50) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
Phenol SCHEMBL27752800 0.81 HPGD (0.51) ALDH1A1TSHRGPR35TDP1KMT2A
Phenol SCHEMBL28068475 0.80 TDP1 (0.52) ALDH1A1TSHRALOX15GPR35TDP1
SCHEMBL1273868 0.80 GPR35 (0.62) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL1273867 0.80 GPR35 (0.62) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
Formic Acid SCHEMBL28829433 0.80 ALDH1A1 (0.48) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL13982734 0.79 GRIN2D (0.42) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
Phenol SCHEMBL27765223 0.78 GPR35 (0.66) ALDH1A1TSHRALOX15GPR35S100A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105621587-B A kind of method using potentiometric titrations degradating chloro nitro-aromatic 浙江大学 2018-01-23 CN claimed
CN-105621587-A Method for degrading chloro-nitroaromatic by using sulfate radicals UNIV ZHEJIANG 2016-06-01 CN claimed
CN-105621587-A Method for degrading chloro-nitroaromatic by using sulfate radicals UNIV ZHEJIANG 2016-06-01 CN disclosed