Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TYR | P14679 | 1/20 | 0.50 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | GLA | P06280 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 4/20 | 0.37 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2154550 | 0.90 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2CA2POLBTYR | |
| SCHEMBL27318671 | 0.89 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2CA2POLBTYR | |
| SCHEMBL2153658 | 0.81 | KIF11 (0.39) | ALDH1A1SMN1; SMN2CA2POLBTYR | |
| SCHEMBL80564 | 0.79 | KDM4E (0.55) | ALDH1A1POLBCYP2C19HPGDKDM4E | |
| SCHEMBL23221325 | 0.78 | HSPA5 (0.49) | ALDH1A1SMN1; SMN2CA2POLBTYR | |
| SCHEMBL28068634 | 0.76 | HSPA5 (0.47) | ALDH1A1SMN1; SMN2HSPA5CYP2C9CYP2C19 | |
| SCHEMBL26064231 | 0.76 | L3MBTL1 (0.33) | ALDH1A1SMN1; SMN2HSPA5CYP2C9CYP2C19 | |
| SCHEMBL16122696 | 0.74 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2CA2CYP2C9CYP2C19 | |
| SCHEMBL25491422 | 0.74 | KDM4E (0.36) | ALDH1A1CYP2C19HPGDKDM4EGLA | |
| SCHEMBL28248528 | 0.74 | GAA (0.36) | ALDH1A1SMN1; SMN2HSPA5CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106083927-A | Phosphinyl amidine compound, metal complex, antigravity system and their oligomeric or purposes of olefin polymerization | 切弗朗菲利浦化学公司 | 2016-11-09 | — | — | CN | disclosed |
| CN-102781949-B | Phosphinyl amidine compounds, metal complexes, catalyst systems, and their use for oligomerizing or polymerizing olefins | 切弗朗菲利浦化学公司 | 2016-07-06 | — | — | CN | disclosed |