Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | LTB4R2 | Q9NPC1 | 5/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7398164 | 0.81 | BCAT2 (0.48) | ALDH1A1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL29502712 | 0.75 | LTB4R2 (0.57) | CES2CES1LTB4R2 | |
| SCHEMBL365731 | 0.75 | LTB4R2 (0.57) | CES2CES1LTB4R2 | |
| SCHEMBL7367739 | 0.75 | BCAT2 (0.35) | SLC6A3ALDH1A1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL10892045 | 0.74 | ALDH1A1 (0.57) | ALDH1A1TRPA1TSHRCES2CES1 | |
| SCHEMBL12494835 | 0.74 | SLC6A3 (0.35) | SLC6A3LTB4R2SLC6A4 | |
| SCHEMBL5902171 | 0.73 | BCAT2 (0.65) | SLC6A3ALDH1A1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL7897093 | 0.73 | BCAT2 (0.42) | SLC6A3ALDH1A1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL7430881 | 0.73 | BCAT2 (0.50) | SLC6A3ALDH1A1TSHRHDAC8HDAC6 | |
| SCHEMBL29390423 | 0.73 | SLC6A3 (0.68) | SLC6A3TSHRLTB4R2SLC6A4HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105622595-A | Novel preparation method of azilsartan medoxomil sylvite and its intermediate | CHONGQING LAND TOWER PHARMACEUTICAL CO LTD | 2016-06-01 | — | — | CN | claimed |
| CN-105622595-A | Novel preparation method of azilsartan medoxomil sylvite and its intermediate | CHONGQING LAND TOWER PHARMACEUTICAL CO LTD | 2016-06-01 | — | — | CN | disclosed |