Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | DRD2 | P14416 | 1/20 | 0.59 |
| ▸ | DRD3 | P35462 | 1/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL720666 | 0.95 | POLB (0.66) | CYP1A2CYP2D6CYP2C9CYP2C19POLB | |
| SCHEMBL19049515 | 0.90 | LMNA (0.61) | CYP1A2CYP2D6CYP2C9CYP2C19POLB | |
| SCHEMBL28701403 | 0.84 | CYP1A2 (0.60) | CYP1A2CYP2D6CYP2C9CYP2C19POLB | |
| SCHEMBL31123005 | 0.83 | SMN1; SMN2 (0.63) | CYP1A2CYP2D6CYP2C9CYP2C19POLB | |
| SCHEMBL179074 | 0.83 | SMN1; SMN2 (0.63) | CYP1A2CYP2D6CYP2C9CYP2C19POLB | |
| SCHEMBL15228755 | 0.82 | CYP1A2 (0.59) | CYP1A2CYP2D6CYP2C9CYP2C19POLB | |
| SCHEMBL8070439 | 0.82 | HTR1A (0.62) | CYP1A2CYP2D6CYP2C9CYP2C19POLB | |
| SCHEMBL875704 | 0.81 | SMN1; SMN2 (0.60) | CYP1A2CYP2D6CYP2C9CYP2C19POLB | |
| SCHEMBL30089495 | 0.81 | SMN1; SMN2 (0.60) | CYP1A2CYP2D6CYP2C9CYP2C19POLB | |
| SCHEMBL874574 | 0.81 | CYP1A2 (0.59) | CYP1A2CYP2D6CYP2C9CYP2C19POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118184588-A | N-aryl/alkyl quinazolinone compound and synthesis method thereof | 陕西科技大学 | 2024-06-14 | — | — | CN | disclosed |
| CN-107337646-B | Method for synthesizing quinazolinone derivative by using methanol as raw material | 南京理工大学 | 2020-04-07 | — | — | CN | disclosed |
| CN-107337646-A | A kind of method using methanol as Material synthesis Quinazol derivative | 南京理工大学 | 2017-11-10 | — | — | CN | disclosed |
| CN-105732519-A | Synthetic method of nitrogenous heterocyclic compound | 武汉理工大学 | 2016-07-06 | — | — | CN | disclosed |