Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | HTT | P42858 | 2/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | DRD2 | P14416 | 1/20 | 0.61 |
| ▸ | DRD3 | P35462 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | HTR1A | P08908 | 3/20 | 0.60 |
| ▸ | HTR7 | P34969 | 3/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28069319 | 0.95 | CYP1A2 (0.64) | POLBMAPTMEN1KMT2AHTT | |
| SCHEMBL19049515 | 0.89 | LMNA (0.61) | POLBMAPTMEN1KMT2AHTT | |
| SCHEMBL8070439 | 0.84 | HTR1A (0.62) | POLBMAPTMEN1KMT2AHTT | |
| SCHEMBL179074 | 0.82 | SMN1; SMN2 (0.63) | POLBMAPTKMT2AHTTSMN1; SMN2 | |
| SCHEMBL31123005 | 0.82 | SMN1; SMN2 (0.63) | POLBMAPTKMT2AHTTSMN1; SMN2 | |
| SCHEMBL15228755 | 0.81 | CYP1A2 (0.59) | POLBMAPTMEN1KMT2AHTT | |
| SCHEMBL8374787 | 0.81 | MAPT (0.62) | POLBMAPTMEN1KMT2AHTT | |
| SCHEMBL3378195 | 0.80 | HDAC3 (0.65) | POLBMAPTMEN1KMT2AHTT | |
| SCHEMBL8433376 | 0.80 | HTR1A (0.58) | POLBMAPTMEN1KMT2AHTT | |
| SCHEMBL874574 | 0.80 | CYP1A2 (0.59) | POLBMAPTKMT2AHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104023535-A | Use of pesticidal active 3-arylquinazolin-4-one derivatives in soil application methods | BASF SE | 2014-09-03 | — | — | CN | claimed |
| US-20140221201-A1 | INSECTICIDAL ACTIVE MIXTURES COMPRISING ARYLQUINAZOLINONE COMPOUNDS | BASF SE (DE) | 2014-08-07 | — | — | US | claimed |
| US-20140213445-A1 | Use of Pesticidal Active 3-Arylquinazolin-4-One Derivatives in Soil Application Methods | BASF SE (DE) | 2014-07-31 | — | — | US | claimed |
| EP-2750503-A1 | INSECTICIDAL ACTIVE MIXTURES COMPRISING ARYLQUINAZOLINONE COMPOUNDS | BASF SE (DE) | 2014-07-09 | — | — | EP | claimed |
| EP-2750507-A2 | AGRICULTURAL MIXTURES COMPRISING ARYLQUINAZOLINONE COMPOUNDS | BASF SE (DE) | 2014-07-09 | — | — | EP | claimed |
| EP-2750506-A2 | USE OF PESTICIDAL ACTIVE 3-ARYLQUINAZOLIN-4-ONE DERIVATIVES IN SOIL APPLICATION METHODS | BASF SE (DE) | 2014-07-09 | — | — | EP | claimed |
| EP-2403837-B1 | 3-ARYLQUINAZOLIN-4-ONE COMPOUNDS FOR COMBATING INVERTEBRATE PESTS | BASF SE (DE) | 2013-12-11 | — | — | EP | claimed |
| WO-2013030319-A2 | USE OF PESTICIDAL ACTIVE 3-ARYLQUINAZOLIN-4-ONE DERIVATIVES IN SOIL APPLICATION METHODS | BASF SE (DE) | 2013-03-07 | — | — | WO | claimed |
| WO-2013030338-A2 | AGRICULTURAL MIXTURES COMPRISING ARYLQUINAZOLINONE COMPOUNDS | BASF SE (DE) | 2013-03-07 | — | — | WO | claimed |
| WO-2013030262-A1 | INSECTICIDAL ACTIVE MIXTURES COMPRISING ARYLQUINAZOLINONE COMPOUNDS | BASF SE (DE) | 2013-03-07 | — | — | WO | claimed |
| US-20120053052-A1 | 3-Arylquinazolin-4-one compounds for combating invertebrate pests | BASF SE (DE) | 2012-03-01 | — | — | US | claimed |
| EP-2403837-A1 | 3-ARYLQUINAZOLIN-4-ONE COMPOUNDS FOR COMBATING INVERTEBRATE PESTS | BASF SE (DE) | 2012-01-11 | — | — | EP | claimed |
| WO-2010100189-A1 | 3-ARYLQUINAZOLIN-4-ONE COMPOUNDS FOR COMBATING INVERTEBRATE PESTS | BASF SE (DE) | 2010-09-10 | — | — | WO | claimed |
| CN-117049997-A | Phenyl trifluoroethyl thioether (sulfoxide) compound and application thereof | 帕潘纳(北京)科技有限公司 | 2023-11-14 | — | — | CN | disclosed |
| EP-3483144-B1 | HETEROCYCLIC COMPOUND AND HARMFUL ARTHROPOD CONTROLLING AGENT CONTAINING SAME | SUMITOMO CHEMICAL CO (JP) | 2023-10-11 | — | — | EP | disclosed |
| CN-104023535-A | Use of pesticidal active 3-arylquinazolin-4-one derivatives in soil application methods | BASF SE | 2014-09-03 | — | — | CN | disclosed |
| EP-0475755-B1 | 3-Aryl-4(3H)quinazolinone CCK antagonists and pharmaceutical formulations thereof | LILLY CO ELI (US) | 1995-09-27 | — | — | EP | disclosed |
| US-5196427-A | Gastrointestinal and central nervous system disorders; hormone inhibitors | ELI LILLY AND COMPANY (US) | 1993-03-23 | — | — | US | disclosed |
| EP-0475755-A1 | 3-Aryl-4(3H)quinazolinone CCK antagonists and pharmaceutical formulations thereof | ELI LILLY AND COMPANY (US) | 1992-03-18 | — | — | EP | disclosed |
| US-5075313-A | For bindign to cholecystokinin receptors | ELI LILLY AND COMPANY (US) | 1991-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140221201-A1 | INSECTICIDAL ACTIVE MIXTURES COMPRISING ARYLQUINAZOLINONE COMPOUNDS | MCU, AGK, NLN | POLB 3710/4885MAPT 3543/4885MEN1 1568/4885 |
| US-20140213445-A1 | Use of Pesticidal Active 3-Arylquinazolin-4-One Derivatives in Soil Application Methods | DDT, TYR, DPYSL3 | POLB 4693/4885MAPT 4447/4885MEN1 2103/4885 |
| US-20120053052-A1 | 3-Arylquinazolin-4-one compounds for combating invertebrate pests | CBR3, CNPY3, RTN3 | POLB 4729/4885MAPT 4831/4885MEN1 3927/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.