Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H3 | Q13133 | 3/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 5/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10099635 | 0.79 | NR1H3 (0.47) | NR1H3NR1H2NPC1RAB9APDE3B | |
| SCHEMBL724249 | 0.78 | PDE3B (0.55) | NR1H3NR1H2NPC1RAB9APDE3B | |
| SCHEMBL27779084 | 0.77 | SIGMAR1 (0.45) | NPC1RAB9AHSD11B1 | |
| SCHEMBL27217302 | 0.76 | BRD4 (0.47) | NR1H3NR1H2NPC1RAB9APDE3B | |
| SCHEMBL5376023 | 0.76 | NPC1 (0.44) | NR1H3NR1H2NPC1RAB9APDE3B | |
| SCHEMBL27517990 | 0.76 | NR1H2 (0.44) | NR1H3NR1H2NPC1RAB9APDE3B | |
| SCHEMBL27447718 | 0.76 | BRD4 (0.47) | NR1H3NR1H2NPC1RAB9APDE3B | |
| SCHEMBL28078869 | 0.76 | LMNA (0.39) | NR1H3NR1H2NPC1RAB9ATSHR | |
| SCHEMBL12759447 | 0.74 | NR1H3 (0.47) | NR1H3NR1H2NPC1RAB9APDE3B | |
| SCHEMBL27779265 | 0.74 | SCN5A (0.43) | NPC1RAB9AHSD11B1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105777646-A | Novel preparation method of 5-iodine-2-phenyl-1-methyl imidazole | 西南科技大学 | 2016-07-20 | — | — | CN | disclosed |
| CN-105753788-A | Preparation method of 1-substituted-2-phenyl-4-idoimidazole | 西南科技大学 | 2016-07-13 | — | — | CN | disclosed |