Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 4/20 | 0.39 |
| ▸ | CTSB | P07858 | 4/20 | 0.39 |
| ▸ | CTSK | P43235 | 3/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 4/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 4/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 4/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 4/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 4/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 3/20 | 0.36 |
| ▸ | CTSV | O60911 | 1/20 | 0.36 |
| ▸ | CTSC | P53634 | 1/20 | 0.36 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19210117 | 0.88 | ADAM17 (0.41) | CTSLCTSBCTSKALDH1A1CYP3A4 | |
| SCHEMBL28318745 | 0.74 | PSEN1 (0.41) | CTSLCTSBCTSKPSEN1PSEN2 | |
| SCHEMBL670182 | 0.70 | CTSC (0.46) | ALDH1A1MAPK1CTSCEPHX2 | |
| SCHEMBL28323025 | 0.70 | CETP (0.44) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL19385743 | 0.69 | OPRM1 (0.46) | CTSLCTSBCTSKALDH1A1CYP3A4 | |
| SCHEMBL28069675 | 0.68 | CTSL (0.44) | CTSLCTSBCTSKALDH1A1CYP3A4 | |
| SCHEMBL18819598 | 0.68 | CTSL (0.44) | CTSLCTSBCTSKALDH1A1CYP3A4 | |
| SCHEMBL668935 | 0.68 | SLC1A2 (0.42) | CTSLCTSBCTSKALDH1A1TSHR | |
| SCHEMBL5899663 | 0.68 | CTSL (0.41) | CTSLCTSBCTSKALDH1A1CYP3A4 | |
| SCHEMBL19601334 | 0.67 | CTSL (0.51) | CTSLCTSBCTSKEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108348525-A | The medical usage of oxipurinol class compound | 广东众生药业股份有限公司 | 2018-07-31 | — | — | CN | disclosed |
| CN-107001371-A | Oxipurinol class compound and its application | 广东众生药业股份有限公司 | 2017-08-01 | — | — | CN | disclosed |
| CN-105566324-A | Hydroxyl purine compound and application thereof | GOOD DOCTOR PHARMACEUTICAL GROUP CO LTD | 2016-05-11 | — | — | CN | disclosed |