Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP3 | O14638 | 1/20 | 0.33 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12640042 | 0.75 | ALDH1A1 (0.34) | — | |
| SCHEMBL956270 | 0.73 | SLC6A4 (0.33) | — | |
| SCHEMBL868907 | 0.72 | PRKCA (0.37) | — | |
| SCHEMBL868908 | 0.72 | PRKCA (0.37) | — | |
| SCHEMBL10362 | 0.72 | — | — | |
| SCHEMBL28412393 | 0.70 | — | — | |
| SCHEMBL14779950 | 0.69 | CA1 (0.45) | ENPP3ENPP1ENPP2 | |
| SCHEMBL18253437 | 0.69 | CYP2C19 (0.33) | — | |
| SCHEMBL2900753 | 0.68 | — | — | |
| SCHEMBL1997388 | 0.68 | CA1 (0.48) | ENPP3ENPP1ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107001371-B | Oxipurinol class compound and its application | 广东众生睿创生物科技有限公司 | 2019-07-05 | — | — | CN | disclosed |
| CN-108348525-A | The medical usage of oxipurinol class compound | 广东众生药业股份有限公司 | 2018-07-31 | — | — | CN | disclosed |
| CN-107001371-A | Oxipurinol class compound and its application | 广东众生药业股份有限公司 | 2017-08-01 | — | — | CN | disclosed |
| CN-105566324-A | Hydroxyl purine compound and application thereof | GOOD DOCTOR PHARMACEUTICAL GROUP CO LTD | 2016-05-11 | — | — | CN | disclosed |