SCHEMBL28069845

SCHEMBL28069845

Cc1ccc(OB(O)O)cc1-c1ccc(CN)cc1

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ST14 Q9Y5Y6 3/20 0.39
AKT2 P31751 1/20 0.38
HRH3 Q9Y5N1 1/20 0.37
CD274 Q9NZQ7 1/20 0.35
F11 P03951 1/20 0.35
MAOB P27338 3/20 0.33
BACE1 P56817 1/20 0.33
NOS3 P29474 1/20 0.33
NOS1 P29475 1/20 0.33
NOS2 P35228 1/20 0.33
TAAR1 Q96RJ0 1/20 0.33
KEAP1 Q14145 1/20 0.33
NFE2L2 Q16236 1/20 0.33
MAPK14 Q16539 1/20 0.33
RXRA P19793 1/20 0.32
RXRB P28702 1/20 0.32
RXRG P48443 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28069904 0.79 HRH3 (0.56) ST14HRH3F11MAOBTAAR1
SCHEMBL3780634 0.77 HRH3 (0.52) AKT2HRH3CD274BACE1NOS3
SCHEMBL3591237 0.77 ST14 (0.50) ST14HRH3F11MAOBKEAP1
SCHEMBL28069848 0.75 TAAR1 (0.50) ST14HRH3F11MAOBTAAR1
Hydrochloric Acid SCHEMBL3457459 0.75 F11 (0.54) ST14HRH3F11MAOBKEAP1
SCHEMBL28067255 0.75 ST14 (0.48) ST14HRH3F11MAOBKEAP1
SCHEMBL22400156 0.74 HRH3 (0.48) AKT2HRH3CD274BACE1NOS3
SCHEMBL29278208 0.71 ST14 (0.41) ST14HRH3F11MAOBNOS3
SCHEMBL21725660 0.71 TAAR1 (0.53) AKT2HRH3CD274MAOBTAAR1
SCHEMBL27936655 0.71 HRH3 (0.45) AKT2HRH3CD274BACE1NOS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103570620-B The luxuriant and rich with fragrance compounds of a kind of 1,12-imino group benzo [c], intermediate and preparation method and application 昆山维信诺显示技术有限公司 2016-06-15 CN disclosed