Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.57 |
| ▸ | MEN1 | O00255 | 8/20 | 0.57 |
| ▸ | POLB | P06746 | 3/20 | 0.57 |
| ▸ | TPMT | P51580 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29141123 | 0.89 | KMT2A (0.56) | KMT2AMEN1POLBALDH1A1L3MBTL1 | |
| SCHEMBL12240557 | 0.85 | CYP3A4 (0.59) | KMT2APOLBALDH1A1L3MBTL1TDP1 | |
| SCHEMBL18778626 | 0.85 | MEN1 (0.56) | KMT2AMEN1POLBTPMTALDH1A1 | |
| SCHEMBL24914750 | 0.83 | TPMT (0.50) | KMT2AMEN1POLBTPMTALDH1A1 | |
| SCHEMBL16397173 | 0.83 | GAA (0.58) | KMT2AMEN1POLBALDH1A1L3MBTL1 | |
| SCHEMBL10148977 | 0.80 | TPMT (0.59) | KMT2AMEN1POLBTPMTALDH1A1 | |
| SCHEMBL26997457 | 0.79 | KMT2A (0.50) | KMT2AMEN1POLBALDH1A1L3MBTL1 | |
| SCHEMBL15587825 | 0.77 | ALDH1A1 (0.51) | KMT2AMEN1POLBALDH1A1L3MBTL1 | |
| SCHEMBL3090260 | 0.77 | POLB (0.67) | KMT2AMEN1POLBALDH1A1L3MBTL1 | |
| SCHEMBL10964661 | 0.76 | L3MBTL1 (0.77) | KMT2AMEN1POLBALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105555766-A | Aminomethyl-biaryl derivatives as complement factor D inhibitors and uses thereof | NOVARTIS AG | 2016-05-04 | — | — | CN | disclosed |