Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 7/20 | 0.53 |
| ▸ | GABRG2 | P18507 | 7/20 | 0.53 |
| ▸ | GABRB3 | P28472 | 7/20 | 0.53 |
| ▸ | GABRA5 | P31644 | 7/20 | 0.53 |
| ▸ | GABRA3 | P34903 | 7/20 | 0.53 |
| ▸ | GABRA2 | P47869 | 6/20 | 0.53 |
| ▸ | GABRP | O00591 | 4/20 | 0.53 |
| ▸ | GABRD | O14764 | 4/20 | 0.53 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.53 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.53 |
| ▸ | GABRA4 | P48169 | 4/20 | 0.53 |
| ▸ | GABRE | P78334 | 4/20 | 0.53 |
| ▸ | GABRA6 | Q16445 | 4/20 | 0.53 |
| ▸ | GABRG1 | Q8N1C3 | 4/20 | 0.53 |
| ▸ | GABRG3 | Q99928 | 4/20 | 0.53 |
| ▸ | GABRQ | Q9UN88 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28292086 | 0.80 | LCK (0.49) | HPGDCYP3A4LCKMAPK1CA12 | |
| SCHEMBL28447307 | 0.79 | CA12 (0.41) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL29721954 | 0.79 | GABRA1 (0.52) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL3830369 | 0.79 | GABRA1 (0.52) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL31017194 | 0.78 | GABRA1 (0.49) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL8344794 | 0.75 | CA12 (0.50) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL30159581 | 0.74 | CREBBP (0.54) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL16881173 | 0.74 | CREBBP (0.54) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL4805737 | 0.74 | SMYD3 (0.51) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL14494403 | 0.73 | CA12 (0.55) | MAPTCYP1A2MAPK1CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103608346-B | As the 7-naphthyridine derivatives of hypoxia inducible factor (HIF) hydroxylase inhibitors | 菲布罗根有限公司 | 2016-06-15 | — | — | CN | disclosed |