Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.47 |
| ▸ | MAOA | P21397 | 4/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.45 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
| ▸ | RXRG | P48443 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 3/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28070012 | 0.89 | KDM4E (0.43) | MAOBMAOAKDM1AMAPK1 | |
| SCHEMBL28069950 | 0.84 | KDM1A (0.45) | MAOBMAOAKDM1AALOX5FFAR1 | |
| SCHEMBL23888261 | 0.76 | S1PR1 (0.51) | MAOBMAOAKDM1AS1PR1S1PR5 | |
| SCHEMBL31703542 | 0.67 | S1PR1 (0.51) | MAOBMAOAKDM1AS1PR1S1PR5 | |
| SCHEMBL31703574 | 0.64 | ALOX5 (0.66) | MAOBMAOAALOX5RXRARXRB | |
| SCHEMBL5089357 | 0.64 | ALOX5 (0.59) | MAOBMAOAALOX5RXRARXRB | |
| SCHEMBL1287464 | 0.64 | KDM1A (1.00) | MAOBMAOAKDM1A | |
| SCHEMBL2551590 | 0.64 | KDM1A (1.00) | MAOBMAOAKDM1A | |
| SCHEMBL2362164 | 0.64 | KDM1A (1.00) | MAOBMAOAKDM1A | |
| Methyl Alcohol SCHEMBL9626623 | 0.63 | RXRA (0.68) | MAOBMAOAALOX5RXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105555365-A | Methods and compositions for modulating cancer stem cells | THE UNIV OF CANBERRA | 2016-05-04 | — | — | CN | disclosed |