Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.66 |
| ▸ | MAOB | P27338 | 7/20 | 0.61 |
| ▸ | MAOA | P21397 | 3/20 | 0.61 |
| ▸ | GRM5 | P41594 | 2/20 | 0.59 |
| ▸ | RXRA | P19793 | 1/20 | 0.59 |
| ▸ | RXRB | P28702 | 1/20 | 0.59 |
| ▸ | RXRG | P48443 | 1/20 | 0.59 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.53 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31703580 | 0.82 | ALOX5 (0.59) | ALOX5MAOBMAOAGRM5RXRA | |
| SCHEMBL5089357 | 0.77 | ALOX5 (0.59) | ALOX5MAOBMAOAGRM5RXRA | |
| SCHEMBL31703542 | 0.76 | S1PR1 (0.51) | ALOX5MAOBMAOAGRM5RXRA | |
| SCHEMBL9627231 | 0.76 | MAOB (0.74) | ALOX5MAOBMAOARXRARXRB | |
| SCHEMBL8935263 | 0.76 | ALOX5 (0.67) | ALOX5MAOBMAOARXRARXRB | |
| SCHEMBL9460359 | 0.75 | GID4 (0.69) | ALOX5MAOBMAOARXRARXRB | |
| SCHEMBL3624161 | 0.75 | MAOB (0.73) | ALOX5MAOBMAOARXRARXRB | |
| SCHEMBL31703392 | 0.74 | RXRA (0.61) | ALOX5MAOBMAOARXRARXRB | |
| SCHEMBL6522344 | 0.74 | RXRA (1.00) | ALOX5MAOBMAOARXRARXRB | |
| SCHEMBL29784197 | 0.74 | RXRA (1.00) | ALOX5MAOBMAOARXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025217513-A1 | ACTIVATION OF PLCG2 AS A THERAPEUTIC STRATEGY FOR THE TREATMENT OF ALZHEIMER'S DISEASE | THE TRUSTEES OF INDIANA UNIVERSITY (US) | 2025-10-16 | — | — | WO | disclosed |