SCHEMBL28070299

SCHEMBL28070299

Cc1ccccc1-c1ccc(N)c(N)c1-c1ccccc1C

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.48
MAOB P27338 1/20 0.48
CD44 P16070 1/20 0.45
CYP3A4 P08684 2/20 0.42
ALDH1A1 P00352 2/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
NPC1 O15118 2/20 0.42
CASP3 P42574 2/20 0.42
RAB9A P51151 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
SENP7 Q9BQF6 2/20 0.42
SENP6 Q9GZR1 2/20 0.42
TSHR P16473 2/20 0.42
MAPK1 P28482 1/20 0.42
HBB P68871 1/20 0.42
TDP1 Q9NUW8 1/20 0.41
HEXA P06865 1/20 0.40
HEXB P07686 1/20 0.40
ADORA2A P29274 2/20 0.38
FGR P09769 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3462071 0.88 CD44 (0.48) MAOAMAOBCD44CYP3A4ALDH1A1
SCHEMBL30714451 0.88 CD44 (0.48) MAOAMAOBCD44CYP3A4ALDH1A1
SCHEMBL30158993 0.87 ALDH1A1 (0.45) MAOAMAOBCD44CYP3A4ALDH1A1
SCHEMBL29447448 0.82 POLB (0.52) MAOAMAOBCD44CYP3A4ALDH1A1
SCHEMBL9296990 0.82 POLB (0.52) MAOAMAOBCD44CYP3A4ALDH1A1
SCHEMBL29372739 0.81 MAOA (0.57) MAOAMAOBCYP3A4ALDH1A1L3MBTL1
SCHEMBL475599 0.81 MAOA (0.57) MAOAMAOBCYP3A4ALDH1A1L3MBTL1
SCHEMBL6932597 0.81 ADORA2A (0.50) MAOACD44CYP3A4ALDH1A1L3MBTL1
SCHEMBL1447534 0.81 MAOA (0.57) MAOAMAOBCYP3A4ALDH1A1L3MBTL1
SCHEMBL31054315 0.78 HEXA (0.47) CD44CYP3A4ALDH1A1L3MBTL1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102076813-B Organic electroluminescent device MERCK PATENT GMBH (DE) 2016-05-18 CN disclosed