Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 5/20 | 0.52 |
| ▸ | JAK2 | O60674 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
| ▸ | FYN | P06241 | 1/20 | 0.48 |
| ▸ | MET | P08581 | 2/20 | 0.47 |
| ▸ | DHFR | P00374 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 2/20 | 0.45 |
| ▸ | HCK | P08631 | 2/20 | 0.45 |
| ▸ | SRC | P12931 | 2/20 | 0.45 |
| ▸ | KDR | P35968 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | XBP1 | P17861 | 1/20 | 0.45 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.45 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28120724 | 0.88 | DHFR (0.52) | HRH4JAK2BRD4DHFRLCK | |
| SCHEMBL28070394 | 0.86 | TTK (0.52) | FYNDHFRKDM4ERAB9AL3MBTL1 | |
| SCHEMBL28298603 | 0.84 | MET (0.48) | JAK2BRD4FYNMETKDM4E | |
| SCHEMBL265154 | 0.80 | DHFR (0.59) | HRH4FYNDHFRKDM4ELCK | |
| SCHEMBL30560046 | 0.80 | DHFR (0.59) | HRH4FYNDHFRKDM4ELCK | |
| SCHEMBL28012222 | 0.79 | HRH4 (0.51) | HRH4DHFRADRA2C | |
| SCHEMBL29213517 | 0.78 | PTK2 (0.49) | HRH4JAK2BRD4FYNDHFR | |
| SCHEMBL30827032 | 0.78 | PTK2 (0.49) | HRH4JAK2BRD4FYNDHFR | |
| SCHEMBL1632115 | 0.76 | JAK2 (0.66) | JAK2BRD4 | |
| SCHEMBL29575830 | 0.75 | JAK2 (0.66) | JAK2BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105682661-A | Certain chemical entities, compositions, and methods | 润新生物公司 | 2016-06-15 | — | — | CN | disclosed |