Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | TPMT | P51580 | 1/20 | 0.58 |
| ▸ | CASP6 | P55212 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MITF | O75030 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CCR6 | P51684 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.48 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11542097 | 0.93 | HPSE (0.56) | MEN1KMT2ATPMTCASP6LMNA | |
| SCHEMBL8184777 | 0.92 | TPMT (0.62) | MEN1KMT2ATPMTCASP6LMNA | |
| SCHEMBL27280423 | 0.84 | LMNA (0.54) | MEN1KMT2ATPMTCASP6LMNA | |
| SCHEMBL14879865 | 0.84 | MAPT (0.50) | MEN1KMT2ATPMTCASP6LMNA | |
| SCHEMBL29155879 | 0.81 | HPSE (0.48) | MEN1KMT2ATPMTCASP6LMNA | |
| SCHEMBL14879694 | 0.80 | HPSE (0.47) | MEN1KMT2ATPMTCASP6LMNA | |
| SCHEMBL11547853 | 0.79 | LMNA (0.52) | MEN1KMT2ATPMTLMNAPOLB | |
| SCHEMBL572967 | 0.79 | LMNA (0.47) | MEN1KMT2ATPMTCASP6LMNA | |
| SCHEMBL11543992 | 0.79 | TPMT (0.54) | MEN1KMT2ATPMTLMNATSHR | |
| SCHEMBL11547921 | 0.79 | ALDH1A1 (0.47) | MEN1KMT2ATPMTCASP6LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105753707-A | Synthesis method for 1,4-bis(2,6-binitro-4-formic acid phenoxy)benzene | 常州大学 | 2016-07-13 | — | — | CN | disclosed |
| CN-105753707-A | Synthesis method for 1,4-bis(2,6-binitro-4-formic acid phenoxy)benzene | 常州大学 | 2016-07-13 | — | — | CN | disclosed |