Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 14/20 | 1.00 |
| ▸ | METAP1 | P53582 | 1/20 | 1.00 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.64 |
| ▸ | IDO1 | P14902 | 4/20 | 0.63 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.63 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.50 |
| ▸ | JAK2 | O60674 | 1/20 | 0.49 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.49 |
| ▸ | PAK4 | O96013 | 1/20 | 0.49 |
| ▸ | PIM1 | P11309 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | GSK3B | P49841 | 1/20 | 0.49 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.49 |
| ▸ | HAO1 | Q9UJM8 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28033548 | 0.78 | METAP2 (0.64) | METAP2METAP1NOTUMIDO1KEAP1 | |
| SCHEMBL29626826 | 0.78 | METAP2 (1.00) | METAP2METAP1NOTUMIDO1KEAP1 | |
| SCHEMBL104083 | 0.78 | METAP2 (0.64) | METAP2METAP1NOTUMIDO1KEAP1 | |
| SCHEMBL3697643 | 0.78 | METAP2 (0.63) | METAP2METAP1NOTUMIDO1KEAP1 | |
| SCHEMBL8221447 | 0.77 | METAP2 (1.00) | METAP2METAP1NOTUMIDO1KEAP1 | |
| SCHEMBL13993856 | 0.76 | METAP2 (1.00) | METAP2METAP1IDO1KEAP1SIRT3 | |
| SCHEMBL8664138 | 0.76 | METAP2 (0.95) | METAP2METAP1NOTUMIDO1KEAP1 | |
| SCHEMBL5025520 | 0.76 | IDO1 (1.00) | METAP2METAP1NOTUMIDO1KEAP1 | |
| SCHEMBL1030506 | 0.74 | METAP2 (0.63) | METAP2METAP1NOTUMIDO1KEAP1 | |
| SCHEMBL28855935 | 0.74 | METAP2 (0.68) | METAP2METAP1NOTUMIDO1KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107674037-A | The method of one kind 5 methyl 2 (triazoles of 2H 1,2,3) benzoic acid of synthesis | 四川大学 | 2018-02-09 | — | — | CN | disclosed |
| CN-105669569-B | A kind of synthetic method of the triazole compounds of NH 1,2,3 | 武汉工程大学 | 2017-12-12 | — | — | CN | disclosed |
| CN-105566235-B | The method of the substep synthesis triazoles of NH 1,2,3 is catalyzed using aluminium salt | 武汉工程大学 | 2017-11-21 | — | — | CN | disclosed |
| CN-105669569-A | Synthesis method of NH-1,2,3-triazole compound | 武汉工程大学 | 2016-06-15 | — | — | CN | disclosed |