Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 9/20 | 1.00 |
| ▸ | NOTUM | Q6P988 | 2/20 | 1.00 |
| ▸ | METAP1 | P53582 | 1/20 | 0.64 |
| ▸ | IDO1 | P14902 | 9/20 | 0.63 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.63 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.53 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28070596 | 0.78 | METAP2 (1.00) | METAP2NOTUMMETAP1IDO1KEAP1 | |
| SCHEMBL28033548 | 0.78 | METAP2 (0.64) | METAP2NOTUMMETAP1IDO1KEAP1 | |
| SCHEMBL104083 | 0.78 | METAP2 (0.64) | METAP2NOTUMMETAP1IDO1KEAP1 | |
| SCHEMBL8221447 | 0.77 | METAP2 (1.00) | METAP2NOTUMMETAP1IDO1KEAP1 | |
| SCHEMBL5025520 | 0.76 | IDO1 (1.00) | METAP2NOTUMMETAP1IDO1KEAP1 | |
| SCHEMBL8664138 | 0.76 | METAP2 (0.95) | METAP2NOTUMMETAP1IDO1KEAP1 | |
| SCHEMBL1030506 | 0.74 | METAP2 (0.63) | METAP2NOTUMMETAP1IDO1KEAP1 | |
| SCHEMBL28855935 | 0.74 | METAP2 (0.68) | METAP2NOTUMMETAP1IDO1KEAP1 | |
| SCHEMBL28741785 | 0.74 | IDO1 (0.65) | METAP2NOTUMMETAP1IDO1KEAP1 | |
| SCHEMBL15507246 | 0.70 | IDO1 (0.62) | METAP2NOTUMMETAP1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122079905-A | Preparation method of alkenyl triazole compound | — | 2026-05-26 | — | — | CN | disclosed |
| CN-114450271-B | Ureas, amino and substituted heteroaryl compounds for Cbl-b inhibition | 纽力克斯治疗公司 | 2024-09-20 | — | — | CN | disclosed |
| EP-4003965-A1 | UREA, AMIDE, AND SUBSTITUTED HETEROARYL COMPOUNDS FOR CBL-B INHIBITION | Nurix Therapeutics, Inc. (US) | 2022-06-01 | — | — | EP | disclosed |
| CN-114450271-A | Ureas, amino and substituted heteroaryl compounds for Cbl-b inhibition | 纽力克斯治疗公司 | 2022-05-06 | — | — | CN | disclosed |