Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 15/20 | 0.95 |
| ▸ | IDO1 | P14902 | 7/20 | 0.95 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.95 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.62 |
| ▸ | METAP1 | P53582 | 1/20 | 0.61 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8221447 | 0.98 | METAP2 (1.00) | METAP2IDO1KEAP1SIRT3METAP1 | |
| SCHEMBL5025520 | 0.77 | IDO1 (1.00) | METAP2IDO1KEAP1SIRT3METAP1 | |
| SCHEMBL29539786 | 0.77 | METAP2 (1.00) | METAP2IDO1KEAP1SIRT3METAP1 | |
| SCHEMBL28058540 | 0.77 | METAP2 (1.00) | METAP2IDO1KEAP1SIRT3METAP1 | |
| SCHEMBL28033548 | 0.76 | METAP2 (0.64) | METAP2IDO1KEAP1SIRT3METAP1 | |
| SCHEMBL104083 | 0.76 | METAP2 (0.64) | METAP2IDO1KEAP1SIRT3METAP1 | |
| SCHEMBL1030506 | 0.76 | METAP2 (0.63) | METAP2IDO1KEAP1SIRT3METAP1 | |
| SCHEMBL29626826 | 0.76 | METAP2 (1.00) | METAP2IDO1KEAP1SIRT3METAP1 | |
| SCHEMBL28070596 | 0.76 | METAP2 (1.00) | METAP2IDO1KEAP1SIRT3METAP1 | |
| SCHEMBL28434910 | 0.75 | METAP2 (0.61) | METAP2IDO1KEAP1SIRT3METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776878-A | CONTAINING ANTISOILANT | THE PROCTER & GAMBLE COMPANY (US) | 1998-07-07 | — | — | US | disclosed |