Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | CNR1 | P21554 | 2/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.40 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11022802 | 0.85 | LMNA (0.56) | LMNACYP2D6KMT2ACNR1CNR2 | |
| SCHEMBL27754462 | 0.83 | LMNA (0.49) | LMNACYP2D6KMT2ACNR1CNR2 | |
| SCHEMBL27993264 | 0.83 | GAA (0.47) | KMT2ACES2MEN1KEAP1NFE2L2 | |
| SCHEMBL11436603 | 0.82 | CYP2D6 (0.74) | LMNACYP2D6KMT2ACNR1CNR2 | |
| SCHEMBL27875739 | 0.81 | LMNA (0.47) | LMNACYP2D6KMT2ACNR1CNR2 | |
| SCHEMBL12199145 | 0.79 | LMNA (0.53) | LMNAKMT2ACNR1CNR2CES2 | |
| SCHEMBL17923689 | 0.79 | LMNA (0.53) | LMNAKMT2ACNR1CNR2CES2 | |
| SCHEMBL7073016 | 0.78 | CNR1 (0.56) | LMNAKMT2ACNR1CNR2CES2 | |
| SCHEMBL28329595 | 0.76 | CYP2D6 (0.57) | LMNACYP2D6KMT2ACNR1CNR2 | |
| SCHEMBL28181393 | 0.75 | ALDH1A1 (0.42) | LMNAKMT2ACNR1CNR2CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105669406-B | The method for preparing 2- hydroxyl -2,2- diphenyl -1- (p-methylphenyl) ethyl ketone | 大丰鑫源达化工有限公司 | 2018-08-03 | — | — | CN | claimed |
| CN-105669406-A | Method for preparation of 2-hydroxy-2,2-diphenyl-1-(p-methylphenyl)ethanone | 双键化工（上海）有限公司 | 2016-06-15 | — | — | CN | claimed |
| CN-105669406-B | The method for preparing 2- hydroxyl -2,2- diphenyl -1- (p-methylphenyl) ethyl ketone | 大丰鑫源达化工有限公司 | 2018-08-03 | — | — | CN | disclosed |
| CN-105669406-A | Method for preparation of 2-hydroxy-2,2-diphenyl-1-(p-methylphenyl)ethanone | 双键化工（上海）有限公司 | 2016-06-15 | — | — | CN | disclosed |