SCHEMBL7073016

SCHEMBL7073016

Cc1ccc(C(C(=O)C(c2ccccc2)c2ccc(C)cc2)c2ccccc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 2/20 0.56
CNR2 P34972 2/20 0.56
LMNA P02545 4/20 0.55
MEN1 O00255 3/20 0.54
KMT2A Q03164 3/20 0.54
L3MBTL1 Q9Y468 2/20 0.48
CES2 O00748 1/20 0.48
CES1 P23141 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
HDAC3 O15379 1/20 0.47
HDAC4 P56524 1/20 0.47
HDAC1 Q13547 1/20 0.47
HDAC7 Q8WUI4 1/20 0.47
HDAC2 Q92769 1/20 0.47
HDAC10 Q969S8 1/20 0.47
HDAC11 Q96DB2 1/20 0.47
HDAC8 Q9BY41 1/20 0.47
HDAC6 Q9UBN7 1/20 0.47
HDAC9 Q9UKV0 1/20 0.47
HDAC5 Q9UQL6 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1551142 0.87 CNR1 (0.56) CNR1CNR2LMNAMEN1KMT2A
SCHEMBL465969 0.86 TDP1 (0.61) CNR1CNR2LMNAMEN1KMT2A
SCHEMBL11641774 0.85 CNR1 (0.54) CNR1CNR2LMNAMEN1KMT2A
Phosphine SCHEMBL28775755 0.84 TDP1 (0.58) CNR1CNR2LMNAMEN1KMT2A
SCHEMBL10965487 0.83 CNR1 (0.53) CNR1CNR2LMNAMEN1KMT2A
SCHEMBL4741657 0.83 LMNA (0.61) CNR1CNR2LMNAMEN1KMT2A
SCHEMBL9307280 0.83 L3MBTL1 (0.48) CNR2MEN1KMT2AL3MBTL1TDP1
SCHEMBL2928039 0.82 L3MBTL1 (0.77) CNR1CNR2LMNAMEN1KMT2A
SCHEMBL7076176 0.82 ACP3 (0.54) MEN1KMT2AL3MBTL1TDP1HDAC3
SCHEMBL13789650 0.80 HDAC4 (0.78) CNR1CNR2LMNAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5284975-A Method of preparing α-d-phenylalkylbenzyl carbinol MALLINCKRODT SPECIALTY CHEMICALS COMPANY (US) 1994-02-08 US claimed
CN-111233599-B Aromatic ring ortho-iodoalkanone and synthetic method and application thereof 兰州大学 2021-07-20 CN disclosed
CN-111233599-A Aromatic ring ortho-iodoalkanone and synthetic method and application thereof 兰州大学 2020-06-05 CN disclosed
US-20130116438-A1 IRIDIUM COMPLEX AND METHOD FOR PRODUCING OPTICALLY ACTIVE COMPOUND TAKASAGO INTERNATIONAL CORPORATION (JP) 2013-05-09 US disclosed
US-20030120088-A1 Optically active azetidincarboxamide-coordinated transition metal complexes SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-06-26 US disclosed
US-6156940-A Process for producing optically active carbinols SUMIKA FINE CHEMICALS COMPANY, LIMITED (JP) 2000-12-05 US disclosed
EP-0713848-B1 Process for producing optically active carbinols SUMIKA FINE CHEMICALS COMPANY (JP) 1999-09-08 EP disclosed
EP-0713848-A1 Process for producing optically active carbinols SUMIKA FINE CHEMICALS Company, Limited (JP) 1996-05-29 EP disclosed
EP-0435687-B1 Process for isomerization of oxime ethers SUMITOMO CHEMICAL CO (JP) 1995-03-29 EP disclosed
US-5284975-A Method of preparing α-d-phenylalkylbenzyl carbinol MALLINCKRODT SPECIALTY CHEMICALS COMPANY (US) 1994-02-08 US disclosed
US-5130486-A A ketoximine ether isomerized using a Lewis acid metal halide SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1992-07-14 US disclosed
EP-0435687-A2 Process for isomerization of oxime ethers SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-07-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130116438-A1 IRIDIUM COMPLEX AND METHOD FOR PRODUCING OPTICALLY ACTIVE COMPOUND PPIP5K2, INF2, IMPDH2 CNR1 3101/4885CNR2 2669/4885LMNA 4866/4885
US-20030120088-A1 Optically active azetidincarboxamide-coordinated transition metal complexes AAAS, AP1M1, AP2A1 CNR1 2669/4885CNR2 3289/4885LMNA 912/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.