Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.45 |
| ▸ | CRHR1 | P34998 | 4/20 | 0.43 |
| ▸ | ALPL | P05186 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | F7 | P08709 | 1/20 | 0.41 |
| ▸ | F3 | P13726 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8746755 | 0.75 | MAPT (0.49) | HSD11B1MAPTHPGDHSP90AA1HSP90AB1 | |
| SCHEMBL31438214 | 0.75 | ERBB2 (0.61) | MAPTHPGDALPL | |
| SCHEMBL4338636 | 0.71 | HSD11B1 (0.47) | HSD11B1HSP90AA1HSP90AB1CRHR1ALPL | |
| SCHEMBL18385896 | 0.71 | NPC1 (0.57) | MAPTHPGDALPL | |
| SCHEMBL8368586 | 0.71 | MAPT (0.49) | HSD11B1MAPTHPGDHSP90AA1HSP90AB1 | |
| SCHEMBL15444885 | 0.70 | HSD11B1 (0.46) | HSD11B1MAPTHPGDHSP90AA1HSP90AB1 | |
| SCHEMBL6101031 | 0.69 | CRHR1 (0.48) | HSD11B1HPGDHSP90AA1HSP90AB1CRHR1 | |
| SCHEMBL29098442 | 0.69 | GUSB (0.51) | HSD11B1MAPTHPGDHSP90AA1HSP90AB1 | |
| SCHEMBL7041005 | 0.69 | HSD11B1 (0.45) | HSD11B1MAPTHPGDHSP90AA1HSP90AB1 | |
| SCHEMBL6101843 | 0.69 | CRHR1 (0.55) | HSD11B1MAPTHPGDHSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105669569-B | A kind of synthetic method of the triazole compounds of NH 1,2,3 | 武汉工程大学 | 2017-12-12 | — | — | CN | disclosed |
| CN-105669569-A | Synthesis method of NH-1,2,3-triazole compound | 武汉工程大学 | 2016-06-15 | — | — | CN | disclosed |