Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 4/20 | 0.42 |
| ▸ | CRHR1 | P34998 | 8/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7046189 | 0.89 | HSD11B1 (0.47) | HSD11B1ALDH1A1HSP90AA1HSP90AB1DPP4 | |
| SCHEMBL6552000 | 0.89 | CNR1 (0.47) | HSD11B1ALDH1A1DPP4HPGD | |
| SCHEMBL3949786 | 0.83 | GUSB (0.43) | HSD11B1ALDH1A1HSP90AA1HSP90AB1DPP4 | |
| SCHEMBL6775223 | 0.82 | CRHR1 (0.42) | HSD11B1ALDH1A1HSP90AA1HSP90AB1DPP4 | |
| SCHEMBL6776302 | 0.75 | CRHR1 (0.45) | DPP4CRHR1 | |
| SCHEMBL27570902 | 0.74 | HSP90AB1 (0.47) | HSP90AA1HSP90AB1DPP4CRHR1HTT | |
| SCHEMBL4973922 | 0.74 | CRHR1 (0.37) | HSD11B1ALDH1A1HSP90AA1HSP90AB1DPP4 | |
| SCHEMBL29098442 | 0.73 | GUSB (0.51) | HSD11B1HSP90AA1HSP90AB1DPP4CRHR1 | |
| SCHEMBL7040999 | 0.73 | CRHR1 (0.44) | DPP4CRHR1 | |
| SCHEMBL7578666 | 0.71 | HSD11B1 (0.50) | HSD11B1ALDH1A1HSP90AA1HSP90AB1DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003007887-A2 | SUBSTITUTED IMIDAZOLES AS CANNABINOID RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2003-01-30 | — | — | WO | disclosed |