Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | TP53 | P04637 | 5/20 | 0.57 |
| ▸ | PARK7 | Q99497 | 3/20 | 0.48 |
| ▸ | TGM2 | P21980 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | CTRC | Q99895 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28070743 | 0.84 | TP53 (0.51) | MAPTTP53PARK7TGM2SMN1; SMN2 | |
| SCHEMBL28070700 | 0.80 | ACHE (0.66) | MAPTTP53TGM2SMN1; SMN2ACHE | |
| SCHEMBL28070671 | 0.78 | TP53 (0.76) | MAPTTP53PARK7SMN1; SMN2ACHE | |
| SCHEMBL28070652 | 0.74 | TP53 (0.65) | MAPTTP53PARK7SMN1; SMN2ACHE | |
| SCHEMBL2459977 | 0.73 | TP53 (0.80) | MAPTTP53PARK7SMN1; SMN2ACHE | |
| SCHEMBL5430327 | 0.73 | CHRM1 (0.63) | MAPTTP53PARK7TGM2ACHE | |
| SCHEMBL5656572 | 0.70 | L3MBTL1 (0.60) | MAPTTP53TGM2SMN1; SMN2CHRM5 | |
| SCHEMBL6095022 | 0.70 | TYR (0.64) | SMN1; SMN2CA12CA2ALDH1A1KMT2A | |
| SCHEMBL18954555 | 0.69 | MAPT (0.47) | MAPTTP53PARK7TGM2SMN1; SMN2 | |
| SCHEMBL11793621 | 0.69 | ALDH1A1 (0.49) | MAPTTP53CA12ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105541808-A | Metronidazole-isatin type compound as well as preparation method and application thereof | UNIV JISHOU | 2016-05-04 | — | — | CN | disclosed |