SCHEMBL28070706

SCHEMBL28070706

CC(=P)C(c1ccccc1)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.44
TDP1 Q9NUW8 1/20 0.44
TSHR P16473 1/20 0.43
HDAC3 O15379 1/20 0.43
HDAC4 P56524 1/20 0.43
HDAC1 Q13547 1/20 0.43
HDAC7 Q8WUI4 1/20 0.43
HDAC2 Q92769 1/20 0.43
HDAC10 Q969S8 1/20 0.43
HDAC11 Q96DB2 1/20 0.43
HDAC8 Q9BY41 1/20 0.43
HDAC6 Q9UBN7 1/20 0.43
HDAC9 Q9UKV0 1/20 0.43
HDAC5 Q9UQL6 1/20 0.43
POLB P06746 2/20 0.42
CTSD P07339 1/20 0.41
LMNA P02545 2/20 0.41
ADRA2A P08913 1/20 0.39
ADRA2C P18825 1/20 0.39
HIF1A Q16665 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL578023 0.78 L3MBTL1 (0.48) L3MBTL1TDP1HDAC3HDAC4HDAC1
SCHEMBL396389 0.74 L3MBTL1 (0.56) L3MBTL1TDP1HDAC3HDAC4HDAC1
SCHEMBL9806266 0.74 HPGD (0.48) L3MBTL1TDP1HDAC3HDAC4HDAC1
Benzene SCHEMBL27414119 0.74 L3MBTL1 (0.56) L3MBTL1TDP1HDAC3HDAC4HDAC1
SCHEMBL15757563 0.72 ADRA2C (0.43) L3MBTL1TDP1TSHRHDAC3HDAC4
Bicarbonate SCHEMBL19031939 0.72 L3MBTL1 (0.54) L3MBTL1TDP1HDAC3HDAC4HDAC1
SCHEMBL29024912 0.72 L3MBTL1 (0.54) L3MBTL1TDP1HDAC3HDAC4HDAC1
SCHEMBL11315563 0.72 TDP1 (0.54) L3MBTL1TDP1TSHRHDAC3HDAC4
SCHEMBL17710384 0.72 L3MBTL1 (0.54) L3MBTL1TDP1HDAC3HDAC4HDAC1
SCHEMBL5013786 0.72 TDP1 (0.54) L3MBTL1TDP1TSHRHDAC3HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103917522-B Process for producing N- (hetero) arylazoles 高砂香料工业株式会社 2016-06-15 CN claimed
CN-109553720-A Polydiene and diene copolymers with organic phosphine function 株式会社普利司通 2019-04-02 CN disclosed
CN-103917522-B Process for producing N- (hetero) arylazoles 高砂香料工业株式会社 2016-06-15 CN disclosed