Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.45 |
| ▸ | CTSD | P07339 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28445550 | 0.85 | PTGS2 (0.52) | CYP2D6ALDH1A1 | |
| SCHEMBL9806266 | 0.78 | HPGD (0.48) | L3MBTL1TDP1HDAC3HDAC4HDAC1 | |
| SCHEMBL396389 | 0.78 | L3MBTL1 (0.56) | L3MBTL1TDP1HDAC3HDAC4HDAC1 | |
| SCHEMBL17710384 | 0.76 | L3MBTL1 (0.54) | L3MBTL1TDP1HDAC3HDAC4HDAC1 | |
| SCHEMBL29024912 | 0.76 | L3MBTL1 (0.54) | L3MBTL1TDP1HDAC3HDAC4HDAC1 | |
| Bicarbonate SCHEMBL19031939 | 0.76 | L3MBTL1 (0.54) | L3MBTL1TDP1HDAC3HDAC4HDAC1 | |
| SCHEMBL15757563 | 0.76 | ADRA2C (0.43) | L3MBTL1TDP1HDAC3HDAC4HDAC1 | |
| SCHEMBL5013786 | 0.76 | TDP1 (0.54) | L3MBTL1TDP1HDAC3HDAC4HDAC1 | |
| SCHEMBL17600356 | 0.75 | TDP1 (0.52) | L3MBTL1TDP1HDAC3HDAC4HDAC1 | |
| SCHEMBL4882534 | 0.74 | LMNA (0.56) | TRPA1LMNAADRA2AADRA2CHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 645 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113264972-B | Method for preparing obeticholic acid | 四川科伦药物研究院有限公司 | 2024-07-12 | — | — | CN | claimed |
| CN-118324823-A | Heterofluorene rare earth compound, preparation method thereof and application thereof in olefin polymerization | 中国科学院长春应用化学研究所 | 2024-07-12 | — | — | CN | claimed |
| WO-2023231529-A1 | CHROMOPHORE COMPOUND AND PREPARATION METHOD THEREFOR, AND APPLICATION OF CHROMOPHORE COMPOUND | 华为技术有限公司 | 2023-12-07 | — | — | WO | claimed |
| WO-2023152711-A1 | PROCESS FOR THE PREPARATION OF CENOBAMATE AND INTERMEDIATES THEREOF | METROCHEM API PVT LTD (IN) | 2023-08-17 | — | — | WO | claimed |
| CN-116510698-A | Adsorption material and preparation method and application thereof | 中国石油化工股份有限公司 | 2023-08-01 | — | — | CN | claimed |
| CN-110862423-B | Synthesis method of alpha-aryl galactosyl carbon glycoside and application of alpha-aryl galactosyl carbon glycoside in pharmacy | 三峡大学 | 2023-05-02 | — | — | CN | claimed |
| US-20230057246-A1 | NOVEL PROCESSES FOR PREPARATION OF TEZACAFTOR | LAURUS LABS LIMITED (IN) | 2023-02-23 | — | — | US | claimed |
| EP-4099991-A1 | NOVEL PROCESSES FOR PREPARATION OF TEZACAFTOR | Laurus Labs Limited (IN) | 2022-12-14 | — | — | EP | claimed |
| CN-113321616-A | Method for synthesizing precursor of Alzheimer's disease beta-amyloid protein deposition imaging drug | 江苏华益科技有限公司 | 2021-08-31 | — | — | CN | claimed |
| WO-2021156811-A1 | NOVEL PROCESSES FOR PREPARATION OF TEZACAFTOR | LAURUS LABS LIMITED (IN) | 2021-08-12 | — | — | WO | claimed |
| US-6084079-A | PROTECTING THE 2'-HYDROXY OR THE 2'- AND 11-HYDROXY POSITIONS WITH SILYL PROTECTING GROUPS AND ALKYLATING THE N-POSITION OF THE DESOSAMINE SUGAR; CHEMICAL INTERMEDIATES FOR PREPARATION OF 8,9-DIDEHYDRO-N-DEMETHYL-6,9-EPOXY-N-ALKYLERYTHROMYCINS | ABBVIE INC. | 2000-07-04 | — | — | US | claimed |
| WO-1999031114-A1 | PROCESS FOR THE PREPARATION OF 6-O-METHYL ERYTHROMYCIN A USING 9-HYDROXY ERYTHROMYCIN DERIVATIVES | ABBOTT LABORATORIES (US) | 1999-06-24 | — | — | WO | claimed |
| EP-0165272-A1 | HETEROCYCLIC SUBSTITUTED PENEMS | SCHERING CORPORATION (US) | 1985-12-27 | — | — | EP | claimed |
| EP-0144041-A1 | Heterocyclic substituted penems | SCHERING CORPORATION (US) | 1985-06-12 | — | — | EP | claimed |
| WO-1985002403-A1 | HETEROCYCLIC SUBSTITUTED PENEMS | SCHERING CORP. (US) | 1985-06-06 | — | — | WO | claimed |
| EP-0021626-B1 | SALTS OF PHOSPHORIC ACID DIESTERS, THEIR PREPARATION AND USE IN MEMBRANES, THE MEMBRANES AND THEIR USE IN CALCIUM ION DETERMINATION, AND THE ELECTRODES CONTAINING THEM | BECKMAN INSTRUMENTS, INC. (US) | 1984-01-18 | — | — | EP | claimed |
| US-4369317-A | CALCIUM ION SELECTIVE MEMBRANE | BECKMAN INSTRUMENTS, INC. (US) | 1983-01-18 | — | — | US | claimed |
| US-4338440-A | CALCIUM ION SELECTIVE MEMBRANE COMPONENT | BECKMAN INSTRUMENTS, INC. (US) | 1982-07-06 | — | — | US | claimed |
| US-4271002-A | Calcium ion-selective electrodes and membrane for use therein | BECKMAN INSTRUMENTS, INC. (US) | 1981-06-02 | — | — | US | claimed |
| EP-0021626-A1 | Salts of phosphoric acid diesters, their preparation and use in membranes, the membranes and their use in calcium ion determination, and the electrodes containing them | BECKMAN INSTRUMENTS, INC. (US) | 1981-01-07 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230057246-A1 | NOVEL PROCESSES FOR PREPARATION OF TEZACAFTOR | CYP3A4, CYP4A11, CYP3A43 | L3MBTL1 4882/4885TDP1 1957/4885HDAC3 750/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.