Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride SCHEMBL28867502 | 0.85 | MGLL (0.42) | MGLLCA12CA7CA14KDM4E | |
| SCHEMBL79194 | 0.85 | — | — | |
| SCHEMBL15386448 | 0.74 | — | — | |
| SCHEMBL21538586 | 0.72 | MGLL (0.33) | MGLLCA12CA7CA14 | |
| Bicarbonate SCHEMBL11609855 | 0.72 | HSD17B10 (0.44) | CA12CA7CA14KDM4E | |
| SCHEMBL29195633 | 0.71 | MGLL (0.36) | MGLLCA12CA7CA14KDM4E | |
| Formic Acid SCHEMBL11221746 | 0.70 | CA12 (0.36) | MGLLCA12CA7CA14KDM4E | |
| SCHEMBL12470747 | 0.69 | CA12 (0.38) | MGLLCA12CA7CA14KDM4E | |
| SCHEMBL30846091 | 0.69 | KDM4E (0.36) | MGLLCA12CA7CA14KDM4E | |
| SCHEMBL3752934 | 0.69 | CA12 (0.38) | MGLLCA12CA7CA14KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105814047-A | Fused tricyclic benzimidazoles derivatives as modulators of TNF activity | UCB生物制药私人有限公司 | 2016-07-27 | — | — | CN | disclosed |