Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | PLK1 | P53350 | 1/20 | 0.60 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.56 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 6/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29489054 | 0.95 | HTT (0.66) | MGAMALOX15HTTPLK1DOT1L | |
| SCHEMBL323178 | 0.95 | HTT (0.66) | MGAMALOX15HTTPLK1DOT1L | |
| Hydrochloric Acid SCHEMBL998803 | 0.93 | HTT (0.64) | MGAMALOX15HTTPLK1DOT1L | |
| Hydrochloric Acid SCHEMBL7309164 | 0.93 | HTT (0.64) | MGAMALOX15HTTPLK1DOT1L | |
| Quinoline SCHEMBL28106687 | 0.90 | ALDH1A1 (0.57) | MGAMALOX15HTTPLK1ALDH1A1 | |
| Terephthalic Acid SCHEMBL27671577 | 0.90 | ALDH1A1 (0.65) | MGAMALOX15HTTPLK1DOT1L | |
| Terephthalic Acid SCHEMBL27671578 | 0.90 | ALDH1A1 (0.65) | MGAMALOX15HTTPLK1DOT1L | |
| Quinoline SCHEMBL28116161 | 0.89 | MGAM (0.84) | MGAMALOX15HTTPLK1DOT1L | |
| Isophthalic Acid SCHEMBL28271214 | 0.87 | ALDH1A1 (0.57) | MGAMALOX15HTTPLK1DOT1L | |
| Quinoline SCHEMBL5874527 | 0.86 | ALDH1A1 (0.65) | MGAMALOX15HTTPLK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107286182-A | Novel oxazolidinone fluoro quinolone derivative and purposes | 李靖 | 2017-10-24 | — | — | CN | claimed |
| CN-103459382-B | For suppressing the heterocyclic compound of PASK | 拜奥埃内杰尼克斯公司 | 2016-06-29 | — | — | CN | claimed |
| CN-107286182-A | Novel oxazolidinone fluoro quinolone derivative and purposes | 李靖 | 2017-10-24 | — | — | CN | disclosed |
| CN-103764641-B | The tricyclic compound of fractional saturation and preparation and application thereof | 扎夫根股份有限公司 | 2016-10-26 | — | — | CN | disclosed |
| CN-103459382-B | For suppressing the heterocyclic compound of PASK | 拜奥埃内杰尼克斯公司 | 2016-06-29 | — | — | CN | disclosed |