Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20861812 | 0.70 | CYP3A4 (0.46) | CYP3A4ALDH1A1HPGDKDM4EHTT | |
| SCHEMBL8525913 | 0.70 | CYP3A4 (0.46) | CYP3A4ALDH1A1HPGDKDM4EHTT | |
| SCHEMBL2813908 | 0.69 | NPC1 (0.38) | ALDH1A1HTTCYP1A2L3MBTL1LMNA | |
| SCHEMBL21868858 | 0.68 | CYP3A4 (0.38) | CYP3A4ALDH1A1HPGDKDM4EHTT | |
| Bromide SCHEMBL12482879 | 0.67 | NPC1 (0.37) | ALDH1A1HTTCYP1A2L3MBTL1LMNA | |
| SCHEMBL8080072 | 0.67 | CYP3A4 (0.38) | CYP3A4ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL146503 | 0.65 | CYP1A2 (0.56) | CYP3A4ALDH1A1HPGDKDM4EHTT | |
| SCHEMBL10282695 | 0.65 | CYP3A4 (0.52) | CYP3A4ALDH1A1HPGDKDM4EHTT | |
| SCHEMBL28662 | 0.65 | CYP3A4 (1.00) | CYP3A4ALDH1A1HPGDKDM4EGAA | |
| SCHEMBL8158727 | 0.65 | MAPT (0.40) | CYP3A4ALDH1A1KDM4EHTTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2495268-B1 | Compositions and articles | DOW GLOBAL TECHNOLOGIES LLC (US) | 2015-07-01 | — | — | EP | disclosed |
| US-9000099-B2 | Functionalized polymers, articles prepared therefrom, and methods for making the same | DOW GLOBAL TECHNOLOGIES LLC (US) | 2015-04-07 | — | — | US | disclosed |
| EP-2170970-B1 | FUNCTIONALIZED POLYMERS AND ARTICLES PREPARED THEREFROM | DOW GLOBAL TECHNOLOGIES LLC (US) | 2014-09-03 | — | — | EP | disclosed |
| EP-2495268-A1 | Compositions and articles | Dow Global Technologies LLC (US) | 2012-09-05 | — | — | EP | disclosed |
| US-20100168343-A1 | FUNCTIONALIZED POLYMERS, ARTICLES PREPARED THEREFROM, AND METHODS FOR MAKING THE SAME | DOW GLOBAL TECHNOLOGIES LLC | 2010-07-01 | — | — | US | disclosed |