Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.39 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2807198 | 0.70 | CYP3A4 (0.48) | CYP3A4ALDH1A1HSD17B10HPGDKDM4E | |
| SCHEMBL20861812 | 0.68 | CYP3A4 (0.46) | CYP3A4ALDH1A1HSD17B10KMT2AHPGD | |
| SCHEMBL4933697 | 0.68 | ALDH1A1 (0.47) | CYP3A4ALDH1A1HSD17B10KMT2ACASP1 | |
| SCHEMBL3370631 | 0.68 | MAPT (0.50) | CYP3A4ALDH1A1HSD17B10KMT2ACASP1 | |
| SCHEMBL4851130 | 0.66 | ADORA2B (0.36) | CYP3A4CSNK2A2CSNK2BCSNK2A1ADORA3 | |
| SCHEMBL146503 | 0.64 | CYP1A2 (0.56) | CYP3A4ALDH1A1KMT2AHPGDKDM4E | |
| SCHEMBL16860619 | 0.63 | — | — | |
| SCHEMBL10282695 | 0.63 | CYP3A4 (0.52) | CYP3A4CSNK2A2CSNK2BCSNK2A1ALDH1A1 | |
| SCHEMBL28662 | 0.63 | CYP3A4 (1.00) | CYP3A4ADORA3ADORA2AADORA2BALDH1A1 | |
| SCHEMBL5929142 | 0.62 | CSNK2A2 (0.52) | CYP3A4CSNK2A2CSNK2BCSNK2A1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5876864-A | Fluorene-based alternating polymers containing acetylene group and electroluminescence element using the same | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY | 1999-03-02 | — | — | US | disclosed |