Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.37 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.37 |
| ▸ | DDR1 | Q08345 | 8/20 | 0.37 |
| ▸ | MLNR | O43193 | 3/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | VEGFA | P15692 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tert-Butyl Formate SCHEMBL27850233 | 0.83 | HCRTR1 (0.43) | HCRTR1HCRTR2PDCD1CD274 | |
| Tert-Butyl Formate SCHEMBL27850236 | 0.82 | DDR1 (0.40) | DDR1 | |
| Tert-Butyl Formate SCHEMBL27850289 | 0.81 | PDCD1 (0.36) | DDR1MLNRHTR7CHRM3PDCD1 | |
| Tert-Butyl Formate SCHEMBL28072121 | 0.80 | TP53 (0.39) | DDR1MLNRCHRM3PDCD1CD274 | |
| Tert-Butyl Formate SCHEMBL27993846 | 0.79 | CXCR4 (0.48) | CHRM3 | |
| SCHEMBL28072231 | 0.78 | ELANE (0.43) | HCRTR1HCRTR2DDR1MLNRHTR7 | |
| SCHEMBL1956172 | 0.77 | VEGFA (0.57) | HCRTR1HCRTR2DDR1HTR7VEGFA | |
| Tert-Butyl Formate SCHEMBL27850889 | 0.76 | HTR7 (0.48) | MLNRHTR7 | |
| Tert-Butyl Formate SCHEMBL27994139 | 0.76 | MGLL (0.47) | DDR1 | |
| Tert-Butyl Formate SCHEMBL28831465 | 0.74 | SIGMAR1 (0.45) | DDR1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102307872-B | BCL-2-selectively apoptosis-inducing agents for the treatment of cancer and immune diseases | ABBVIE 公司 | 2016-06-15 | — | — | CN | disclosed |